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DOI: 10.1055/a-2512-5145
A new innovative imaging modality: “extended reality” in endoscopic ultrasonography
Endoscopic ultrasonography (EUS) is essential for management of pancreaticobiliary diseases; it involves operating the endoscope, interpreting the EUS images, comparing them with other images, and considering needle biopsy or surgery. In addition, the anatomy of each patient must be considered; however, attaining an accurate understanding is a major challenge for trainees.
Extended reality (XR) technology is increasingly being used in medical settings [1] [2] [3] [4]. It allows users to grasp and view a three-dimensional (3D) image from various angles, which enables a sensory understanding in conjunction with endoscopic imaging. We believe that XR support can significantly enhance EUS comprehension and training. We here report a case in which EUS was performed with XR navigation support.
A 67-year-old man underwent EUS for suspicion of a serous cystic neoplasm ([Fig. 1]). 3D models were constructed through contrast-enhanced computed tomography (CT) and magnetic resonance cholangiopancreatography (MRCP) using SYNAPSE VINCENT (Fujifilm Medical Co., Ltd., Tokyo, Japan). The models were uploaded into the Holoeyes MD system (Holoeyes Inc., Tokyo, Japan) and visualized as 3D holograms in real space through the see-through “HoloLens 2” goggles (Microsoft Corp., Redmond, Washington, USA), allowing simultaneous viewing of the ultrasound monitor and 3D hologram ([Fig. 2]; [Video 1]). Changing the angle of the 3D image to match that of the EUS image made understanding the depictions of the organs easier. Furthermore, trainees and experts could view the same 3D hologram simultaneously in a virtual session, which proved effective for teaching and reviewing ([Fig. 3]). By adding a hologram of the endoscope, understanding its movement using the goggles became possible ([Fig. 4]).








Qualität:
We performed EUS safely with the XR navigation system, allowing for an intuitive understanding of the 3D structure of the organs. This system was also effective for teaching and review purposes. The new method supported by XR could be a breakthrough in this field.
Endoscopy_UCTN_Code_TTT_1AS_2AD
E-Videos is an open access online section of the journal Endoscopy, reporting on interesting cases and new techniques in gastroenterological endoscopy. All papers include a high-quality video and are published with a Creative Commons CC-BY license. Endoscopy E-Videos qualify for HINARI discounts and waivers and eligibility is automatically checked during the submission process. We grant 100% waivers to articles whose corresponding authors are based in Group A countries and 50% waivers to those who are based in Group B countries as classified by Research4Life (see: https://www.research4life.org/access/eligibility/).
This section has its own submission website at https://mc.manuscriptcentral.com/e-videos.
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Conflict of Interest
The authors declare that they have no conflict of interest.
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References
- 1 Tokunaga T, Sugimoto M, Saito Y. et al. Intraoperative holographic image-guided surgery in a transanal approach for rectal cancer. Langenbecks Arch Surg 2022; 407: 2579-2584
- 2 Saito Y, Sugimoto M, Imura S. et al. Intraoperative 3D hologram support with mixed reality techniques in liver surgery. Ann Surg 2020; 271: E4-E7
- 3 Ryu S, Kitagawa T, Goto K. et al. Intraoperative holographic guidance using virtual reality and mixed reality technology during laparoscopic colorectal cancer surgery. Anticancer Res 2022; 42: 4849-4856
- 4 Ishikawa-Kakiya Y, Maruyama H, Tanoue K. et al. Using a new, innovative “mixed reality” technology in endoscopic retrograde cholangiopancreatography. Endoscopy 2024; 56: E901-E902
Correspondence
Publikationsverlauf
Artikel online veröffentlicht:
31. Januar 2025
© 2025. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/).
Georg Thieme Verlag KG
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References
- 1 Tokunaga T, Sugimoto M, Saito Y. et al. Intraoperative holographic image-guided surgery in a transanal approach for rectal cancer. Langenbecks Arch Surg 2022; 407: 2579-2584
- 2 Saito Y, Sugimoto M, Imura S. et al. Intraoperative 3D hologram support with mixed reality techniques in liver surgery. Ann Surg 2020; 271: E4-E7
- 3 Ryu S, Kitagawa T, Goto K. et al. Intraoperative holographic guidance using virtual reality and mixed reality technology during laparoscopic colorectal cancer surgery. Anticancer Res 2022; 42: 4849-4856
- 4 Ishikawa-Kakiya Y, Maruyama H, Tanoue K. et al. Using a new, innovative “mixed reality” technology in endoscopic retrograde cholangiopancreatography. Endoscopy 2024; 56: E901-E902







