RSS-Feed abonnieren

DOI: 10.1055/a-2563-1474
Novel endoscopic full-thickness resection device for colon polyp resection
Endoscopic full-thickness resection (EFTR) allows for the management of scarred and fibrotic lesions that are not amenable to endoscopic mucosal resection or endoscopic submucosal dissection (ESD). Two main methods of performing EFTR include exposed and nonexposed EFTR. In exposed EFTR, the lesion is resected followed by defect closure. In nonexposed EFTR, the defect is closed prior to resection of the lesion.
The Padlock FTR System (Steris, Mentor, Ohio, USA) is a novel full-thickness resection (FTR) device that includes a Padlock design clip to achieve nonexposed EFTR and then uses a pre-loaded snare to resect the lesion ([Fig. 1]). To the best of our knowledge, we show the first reported case of in-human use of this device ([Video 1]).


Qualität:
A 60-year-old man with a history of >20 polyps and prior ESD for three 4- to 6-cm rectosigmoid polyps presented for endoscopic resection of a rectosigmoid polyp adjacent to a prior ESD resection site. A 20-mm sessile polyp was found in the sigmoid colon next to a previously placed cinch at the site of a prior polyp resection. Given extensive scarring at the site, the decision was made to pursue EFTR. The polyp was successfully resected using this novel FTR device ([Fig. 2]). No adverse events occurred. Examination of the resection site showed the fatty patch, consistent with full-thickness resection, and the clip in place ([Fig. 3]). Pathology revealed a well-differentiated, invasive adenocarcinoma with a depth of submucosal invasion of 600 microns ([Fig. 4]). Deep and lateral margins were negative (R0 resection) for dysplasia.






This device could be a useful tool in the armamentarium for EFTR of previously manipulated colon polyps and lesions with superficial submucosal invasion. Further reports are needed to confirm its safety and efficacy.
Endoscopy_UCTN_Code_TTT_1AQ_2AD_3AF
E-Videos is an open access online section of the journal Endoscopy, reporting on interesting cases and new techniques in gastroenterological endoscopy. All papers include a high-quality video and are published with a Creative Commons CC-BY license. Endoscopy E-Videos qualify for HINARI discounts and waivers and eligibility is automatically checked during the submission process. We grant 100% waivers to articles whose corresponding authors are based in Group A countries and 50% waivers to those who are based in Group B countries as classified by Research4Life (see: https://www.research4life.org/access/eligibility/).
This section has its own submission website at https://mc.manuscriptcentral.com/e-videos.
#
Conflict of Interest
M. B. is a consultant for Boston Scientific, Steris Endoscopy, and a paid speaker for Cook Medical. No other authors have conflicts of interest to disclose.
Correspondence
Publikationsverlauf
Artikel online veröffentlicht:
09. April 2025
© 2025. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/).
Georg Thieme Verlag KG
Oswald-Hesse-Straße 50, 70469 Stuttgart, Germany







