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Synthesis
DOI: 10.1055/a-2685-9083
Paper
Published as part of the Special Issue in Honor of Prof. Franziska Schoenebeck, the 2025 Women in Chemistry Award Winner

Desaturation of Amides via Bismuth Photocatalysis

Autor*innen

  • Byeongdo Roh 

    1   Department of Organometallic Chemistry, Max-Planck-Institut für Kohlenforschung, Kaiser-Wilhelm-Platz, 1, 45470 Mülheim an der Ruhr, Germany

  • Josep Cornella 

    1   Department of Organometallic Chemistry, Max-Planck-Institut für Kohlenforschung, Kaiser-Wilhelm-Platz, 1, 45470 Mülheim an der Ruhr, Germany

Gefördert durch: Verband der Chemischen Industrie
Gefördert durch: Max-Planck-Gesellschaft
Gefördert durch: Novartis Early Career Award Foundation
Gefördert durch: Deutsche Forschungsgemeinschaft EXC 2033-390677874-RESOLV
The financial support for this work was provided by Max-Planck-Gesellschaft, Max-Planck-Institut für Kohlen-forschung, Fonds der Chemischen Industrie (FCI-VCI), NECA foundation, and by the Deutsche Forschungsge-meinschaft (DFG, German Research Foundation) under Germany’s Excellence Strategy - EXC 2033-390677874 -RESOLV.
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Graphical Abstract

Erratum zu diesem Artikel:

Correction: Desaturation of Amides via Bismuth PhotocatalysisSynthesis eFirst
DOI: 10.1055/a-2736-9357

Abstract

Bismuth redox catalysis has been intensively developed in recent years, enabling diverse transformations that were previously thought to be achievable only through transition metal catalysis. In this study, we present the desaturation of amides to generate the enamides, an important structural motif in pharmaceuticals, via bismuth photocatalysis. The protocol involves a combination of unique mechanistic steps recently uncovered for bismuth thus allowing for the translation of a canonical transition metal–mediated transformation into a main group–based catalytic system.

Keywords

Bismuth - Low-valent bismuth - Bismuth redox catalysis - Bismuth photocatalysis - Desaturation - Amides

Supplementary Material



Publikationsverlauf

Eingereicht: 23. Juni 2025

Angenommen nach Revision: 18. August 2025

Accepted Manuscript online:
18. August 2025

Artikel online veröffentlicht:
02. Oktober 2025

© 2025. Thieme. All rights reserved.

Georg Thieme Verlag KG
Oswald-Hesse-Straße 50, 70469 Stuttgart, Germany

 

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