A General Procedure to Access
Methylene Ether Isonitrile Derivatives

Rebecca L. Grange; Craig M. Williams; Lin Dong; Victoria A. Gordon

doi:10.1055/s-0028-1083143

PAPER

A General Procedure to Access Methylene Ether Isonitrile Derivatives

Rebecca L. Grange^a, Craig M. Williams*^a, Lin Dong^a, Victoria A. Gordon^b
^a School of Molecular and Microbial Sciences, University of Queensland, Brisbane 4072, Australia
Fax: +61(7)33654299; e-Mail: c.williams3@uq.edu.au;
^b EcoBiotics Limited, PO Box 1, Yungaburra 4884, Australia

Abstract

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Abstract

Isonitriles are essential building blocks for multicomponent reactions. A convenient and simple two-step synthesis of the little known methylene ether isonitrile derivatives is presented.

Key words

formamide - dehydration - isonitrile/isocyanide - multicomponent reactions

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