An Improved Process for the Synthesis
of 4H-Imidazo[1,5-a][1,4]benzo­diazepines

Jie Yang; Yun Teng; Shamim Ara; Sundari Rallapalli; James M. Cook

doi:10.1055/s-0028-1083358

PSP

An Improved Process for the Synthesis of 4H-Imidazo[1,5-a][1,4]benzodiazepines

Jie Yang, Yun Teng, Shamim Ara, Sundari Rallapalli, James M. Cook*
Department of Chemistry, University of Wisconsin-Milwaukee, Milwaukee, WI 53211, USA
Fax: +1(414)2295530; e-Mail: capncook@uwm.edu;

Abstract

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Abstract

The construction of CNS active imidazo[1,5-a][1,4]benzodiazepines has been improved in a one-pot annulation process.

Key words

GABA_A/Bz receptors - imidazo[1,5-a][1,4]benzodiazepines - ethyl isocyanoacetate - annulation

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References

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An Improved Process for the Synthesis of 4H-Imidazo[1,5-a][1,4]benzo­diazepines

An Improved Process for the Synthesis of 4H-Imidazo[1,5-a][1,4]benzodiazepines