Antioxidative Phenylpropanoid-Substituted Epicatechin Glycosides from Parabarium huaitingii

Abstract

Three new phenylpropanoid-substituted epicatechin glycosides, namely parabarosides A – C (1–3), together with three known compounds, 5-caffeoylquinic acid (4), 5-caffeoylshikimic acid (5), and 3,4-dicaffeoylquinic acid (6), were obtained from the plant Parabarium huaitingii. Their structures were determined and full assignments of ¹H- and ¹³C‐NMR spectroscopic data were achieved by analyses of 1D- and 2D‐NMR, mass, and CD spectra. The oxygen radical absorbance capacity (ORAC) assay was applied to evaluate their antioxidative capacity in vitro, which revealed that 1–6 showed strong antioxidative properties.

Key words

Parabarium huaitingii - Apocynaceae - phenylpropanoid‐substituted epicatechin glycosides - natural polyphenols - antioxidative activities

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