Asymptomatic Paraganglioma of the Posterior Mediastinum Misdiagnosed Until Operation

Abstract

A 23-year-old female patient was treated for a posterior mediastinal tumor of unknown histology. Her systemic blood pressure increased rapidly to a critical level immediately after starting surgical manipulation of the tumor, which was suggestive of a hyperfunctioning pheochromocytoma. The tumor was removed after controlling the blood pressure and was histologically diagnosed as an extra-adrenal pheochromocytoma. Further postoperative investigations showed the tumor to be a sporadic type through further postoperative investigations and the patient had subsequently an uneventful course.

Key words

Pheochromocytoma - posterior mediastinal tumor - paraganglioma

Reference

• 1 Spector J A, Willis D N, Ginsburg H B. Paraganglioma (pheochromocytoma) of the posterior mediastinum: a case report and review of the literature.  J Pediatr Surg. 2003;  38 1114-1116
• 2 Bouhouch A, Hendriks J M, Lauwers P R, De Raeve H R, Van Schil P E. Asymptomatic pheochromocytoma in the posterior mediastinum.  Acta Chir Belg. 2007;  107 465-467
• 3 Sawka A M, Gafni A, Thabane L, Young Jr W F. The economic implications of three biochemical screening algorithms for pheochromocytoma.  J Clin Endocrinol Metab. 2004;  89 2859-2866
• 4 Sahin-Akyar G, Erden I, Yağci C, Akyar S, Erekul S. Magnetic resonance imaging findings of a non-functional mediastinal paraganglioma with an unusual presentation.  Eur Radiol. 1997;  7 1114-1116
• 5 Brown M L, Zayas G E, Abel M D, Young Jr W F, Schaff H V. Mediastinal paragangliomas: the Mayo Clinic experience.  Ann Thorac Surg. 2008;  86 946-951
• 6 Wright C D, Mathisen D J. Mediastinal tumors: diagnosis and treatment.  World J Surg. 2001;  25 204-209