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Synthesis 2009(20): 3405-3410  
DOI: 10.1055/s-0029-1216962
PAPER
© Georg Thieme Verlag Stuttgart ˙ New York

A New Approach to the Synthesis of 3-Substituted 4-(Diethoxy­phosphoryl)isoxazoles from 3-Azidoalka-1,3-dienylphosphonates

Valery K. Brel*
Institute of Physiologically Active Compounds of Russian Academy of Sciences, Chernogolovka, Moscow region 142432, Russian Federation
Fax: +7(496)5249508; e-Mail: brel@ipac.ac.ru;
Further Information

Publication History

Received 11 March 2009
Publication Date:
21 August 2009 (online)

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Abstract

New 3-azidoalka-1,3-dienylphosphonates were synthesized by a convenient and efficient method. These compounds are useful as intermediates in the preparation of 3-(3-aryl-4,5-di­hydroisoxazol-5-yl)- and 3-alkenyl-4-(diethoxyphosphoryl)isoxazoles.

Key words

allenes - azides - isoxazoles nitrile oxides - phosphorus

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