Simple and Efficient Access
to 3-Ethoxycarbonylpyrroles, Benzofurans, and Naphthofurans

Camila G. Pancote; Bruno S. de Carvalho; Cibele V. Luchez; João P. S. Fernandes; Mario J. Politi; Carlos A. Brandt

doi:10.1055/s-0029-1217053

PAPER

Simple and Efficient Access to 3-Ethoxycarbonylpyrroles, Benzofurans, and Naphthofurans

Camila G. Pancote^a, Bruno S. de Carvalho^b, Cibele V. Luchez^b, João P. S. Fernandes^a, Mario J. Politi^b, Carlos A. Brandt*^c
^a Departamento de Farmácia, Faculdade de Ciências Farmacêuticas, Universidade de São Paulo, 05508-900 São Paulo, SP, Brazil
^b Departamento de Bioquímica, Instituto de Química, Universidade de São Paulo, 05508-900 São Paulo, SP, Brazil
^c Instituto Butantan,, Av. Vital Brazil 1500, 05503-900 São Paulo, SP, Brazil
e-Mail: cabrandt@usp.br;

Abstract

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Abstract

An efficient method was developed for the synthesis of pyrrole and furan derivatives from enamines, phenols, and naphthols. The key steps involve iodocyclization and alumina-induced dehydroiodination reactions.

Key words

alumina - dehydroiodination - heterocycles - iodocyclization - ultrasound

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Referenzen

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