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Synthesis 2010(5): 863-869
DOI: 10.1055/s-0029-1218620
DOI: 10.1055/s-0029-1218620
PAPER
© Georg Thieme Verlag
Stuttgart ˙ New YorkSynthesis of Azepine- and Azocine-Annulated Heterocycles by Aromatic Aza-Claisen Rearrangement and Ring-Closing Metathesis
Weitere Informationen
Received
2 November 2009
Publikationsdatum:
22. Dezember 2009 (online)
Publikationsverlauf
Publikationsdatum:
22. Dezember 2009 (online)

Abstract
Syntheses of hitherto unreported azepine- and azocine-annulated heterocycles have been developed in excellent yields via a catalyzed aromatic aza-Claisen rearrangement followed by ring-closing metathesis using Grubbs first-generation catalyst.
Key words
azepine - azocine - aza-Claisen rearrangement - ring-closing metathesis
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