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Synthesis 2010(5): 863-869  
DOI: 10.1055/s-0029-1218620
PAPER
© Georg Thieme Verlag Stuttgart ˙ New York

Synthesis of Azepine- and Azocine-Annulated Heterocycles by Aromatic Aza-Claisen Rearrangement and Ring-Closing Metathesis

K. C. Majumdar*, Srikanta Samanta, Buddhadeb Chattopadhyay, Raj Kumar Nandi
Department of Chemistry, University of Kalyani, Kalyani 741235, W.B., India
e-Mail: kcm_ku@yahoo.co.in;
Further Information

Publication History

Received 2 November 2009
Publication Date:
22 December 2009 (online)

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Abstract

Syntheses of hitherto unreported azepine- and azocine-annulated heterocycles have been developed in excellent yields via a catalyzed aromatic aza-Claisen rearrangement followed by ring-closing metathesis using Grubbs first-generation catalyst.

Key words

azepine - azocine - aza-Claisen rearrangement - ring-closing metathesis

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