Pfefferminzöl beim Reizdarmsyndrom – ein Update

Zusammenfassung

Neuere Untersuchungen bestätigen, dass Pfefferminzöl eine sinnvolle Option in der Therapie des Reizdarmsyndroms ist. Die spasmolytische Wirkung des Pfefferminzöls konnte sowohl in vitro an isolierten Darmsegmenten als auch in vivo an gesunden Probanden und in der Diagnostik des Gastrointestinaltrakts gezeigt werden. Die Hauptkomponente des Öls, Menthol, trägt wesentlich zu seiner spasmolytischen Wirkung bei. In der Behandlung des Reizdarmsyndroms war Pfefferminzöl in kurz- und mittelfristigen klinischen Studien Placebo überlegen.

Summary

Peppermint oil in the treatment of irritable bowel syndrome. An update

Recent investigations confirm that the essential oil of peppermint is a reasonable therapeutic option in the treatment of irritable bowel syndrome. Spasmolytic effects of the essential oil have been demonstrated both in vitro on isolated gut segments and in vivo on healthy voluteers and in gastrointestinal diagnosis. Menthol, the main component of peppermint oil, contributes considerably to its spasmolytic effect. Peppermint oil proved to be superior to a placebo in the treatment of irritable bowel syndrome in short-term and medium-term studies.

Mentha x piperita L. - Pfefferminze - ätherisches Öl - Übersicht - Reizdarmsyndrom

Mentha x piperita L. - peppermint - essential oil - review - irritable bowel syndrome

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1 einbezogen in statistische Metaanalyse (8);

2 vs. Stress-Management-Therapie;

3 28–56 d Follow up;

4 Gastrointestinal Symptom Rating Scale