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DOI: 10.1055/s-0029-1241028
© Georg Thieme Verlag KG Stuttgart · New York
Minimized Extracorporeal Circulation in Coronary Artery Bypass Surgery Is Equivalent to Standard Extracorporeal Circulation in Patients with Reduced Left Ventricular Function
Publication History
received August 17, 2009
Publication Date:
31 May 2010 (online)
![](https://www.thieme-connect.de/media/thoracic/201004/lookinside/thumbnails/10.1055-s-0029-1241028-1.jpg)
Abstract
Background: Minimized extracorporeal circulation (MECC) is a promising alternative to standard extracorporeal circulation (ECC) and its use is increasing in routine coronary bypass surgery. We analyzed the clinical outcome of patients with reduced left ventricular function who underwent coronary artery bypass surgery with MECC or with standard ECC. Methods: From January 2003 to September 2008, 238 patients with a left ventricular function < 30 % underwent bypass surgery with ECC or MECC. The primary end point of our retrospective observational study was 30-day mortality. Secondary endpoints were the transfusion requirements, as well as intensive care and the in-hospital course. Results: Demographic data, comorbidities and left ventricular function were similar in the study groups. MECC patients had a tendency towards a lower 30-day mortality rate, a better postoperative renal function and reduced ventilation times. Extracorporeal circulation time and postoperative high-dose inotropic support were significantly lower in the MECC group, while the stays in the intensive care unit and in hospital were comparable between the two groups. In our study, age in the ECC group, and previous infarction and New York Heart Association grade IV in the MECC group were preoperative risk factors associated with a higher mortality. Conclusion: Coronary bypass surgery using MECC is feasible and safe for patients with severely impaired left ventricular function. It is a promising alternative to ECC with a low mortality rate and a more favorable postoperative course.
Key words
cardiomyopathy - cardiovascular surgery - coronary bypass surgery
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Thomas Puehler, MD
Department of Cardiothoracic Surgery
Medical Center University Regensburg
Franz-Josef-Strauss-Allee 11
93053 Regensburg
Germany
Phone: +49 94 19 44 98 24
Fax: +49 94 19 44 98 11
Email: thomas.puehler@klinik.uni-regensburg.de