Aktueller Stand der Mikro-CT in der experimentellen Kleintierbildgebung

Zusammenfassung

Die Mikro-CT (µCT) hat sich in den letzten Jahren zu einem akzeptierten Forschungsinstrument für die nichtinvasive Bildgebung von Kleintieren entwickelt. Die vorliegende Übersichtsarbeit erläutert die technischen Grundlagen der µCT, beschreibt die bisher erfolgreich mittels µCT bearbeiteten Fragestellungen und geht auf Limitationen ein, welche bei der Planung und Durchführung von µCT-gestützer Bildgebung von Relevanz sind.

Abstract

The number of publications describing the use of micro-computed tomography (µCT) for preclinical in vivo imaging of small animals has risen considerably within the last few years. The purpose of this review is to familiarize the reader with the basic principles of µCT, to present successful experimental approaches in order of the evaluated organ system, and to highlight limitations that need to be considered when planning µCT-based studies.

Key words

CT - experimental - in vivo - small animal - micro-CT

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