DMW - Deutsche Medizinische Wochenschrift, Table of Contents Dtsch Med Wochenschr 2010; 135(48): 2417-2419DOI: 10.1055/s-0030-1247875 Aktuelle Diagnostik & Therapie | Review article Hypertensiologie, Diabetologie © Georg Thieme Verlag KG Stuttgart · New York Neue Zielblutdruckwerte in der antihypertensiven Therapie diabetischer Patienten? New targets for blood pressure lowering in diabetic patients?U. Kintscher1 1Center for Cardiovascular Research (CCR), Institut für Pharmakologie, Charité – Universitätsmedizin Berlin Recommend Article Abstract Buy Article Schlüsselwörter Diabetes - Hypertonie - Blutdrucksenkung - Zielwerte Keywords diabetes - hypertension - blood pressure lowering - target values Full Text References Literatur 1 The ACCORD Study Group . Effects of intensive blood-pressure control in type 2 diabetes mellitus. N Engl J Med. 2010; 362 1575-1585 2 Berthold H K, Gouni-Berthold I, Bestehorn K P, Bohm M, Krone W. Kardiovaskuläre Risikofaktoren bei Typ-2-Diabetikern in Deutschland – ein Versorgungsparadox. Dtsch Ärztebl. 2007; 104 A861-867 3 Cooper-DeHoff R M, Gong Y, Handberg E M. et al . Tight blood pressure control and cardiovascular outcomes among hypertensive patients with diabetes and coronary artery disease. J Amer Med Ass. 2010; 304 61-68 4 Kannel W B, Wilson P W, Zhang T J. The epidemiology of impaired glucose tolerance and hypertension. Am Heart J. 1991; 121 1268-1273 5 Mancia G, De Backer G, Dominiczak A. et al . 2007 Guidelines for the management of arterial hypertension. J Hypertens. 2007; 25 1105-1187 6 Mancia G, Laurent S, Agabiti-Rosei E. et al . Reappraisal of European guidelines on hypertension management: a European Society of Hypertension Task Force document. J Hypertens. 2009; 27 2121-2158 7 Messerli F H, Mancia G, Conti C R. et al . Dogma disputed: can aggressively lowering blood pressure in hypertensive patients with coronary artery disease be dangerous?. Ann Intern Med. 2006; 144 884-893 8 Patel A, MacMahon S, Chalmers J. et al . Effects of a fixed combination of perindopril and indapamide on macrovascular and microvascular outcomes in patients with type 2 diabetes mellitus (the ADVANCE trial): a randomised controlled trial. Lancet. 2007; 370 829-840 9 Patel A, MacMahon S, Chalmers J. et al . Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes. N Engl J Med. 2008; 358 2560-2572 10 Ryden L, Standl E. et al . Guidelines on diabetes, pre-diabetes, and cardiovascular diseases: executive summary. Eur Heart J. 2007; 28 88-136 11 Schrier R W, Estacio R O, Esler A, Mehler P. Effects of aggressive blood pressure control in normotensive type 2 diabetic patients on albuminuria, retinopathy and strokes. Kidney Int. 2002; 61 1086-1097 12 Stamler J, Vaccaro O, Neaton J D, Wentworth D. Diabetes, other risk factors, and 12-yr cardiovascular mortality for men screened in the Multiple Risk Factor Intervention Trial. Diabetes Care. 1993; 16 434-444 13 Tarnow L, Rossing P, Gall M A, Nielsen F S, Parving H H. Prevalence of arterial hypertension in diabetic patients before and after the JNC-V. Diabetes Care. 1994; 17 1247-1251 14 UK Prospective Diabetes Study Group . Tight blood pressure control and risk of macrovascular and microvascular complications in type 2 diabetes: UKPDS 38. Brit Med J. 1998; 317 703-713 Prof. Dr. med. Ulrich Kintscher Center for Cardiovascular Research (CCR)Institut für PharmakologieCharité – Universitätsmedizin Berlin Hessische Str. 3–4 10115 Berlin Phone: 030/450525276 Fax: 030/450525901 Email: ulrich.kintscher@charite.de