Download PDF
kleintier konkret 2010; 13(02): 11-21
DOI: 10.1055/s-0030-1248856
Hund und Katze
CVE
Enke Verlag in MVS Medizinverlage Stuttgart GmbH & Co. KG Stuttgart

Inhalationsnarkose mit Isofluran oder Sevofluran – Wie lässt sich das Risiko von Nebenwirkungen reduzieren?

Michaele Alef
,
Susanne Pfeifer
Further Information

Publication History

Publication Date:
26 April 2010 (online)

Also available at
    Permissions and Reprints All articles of this category

Die Inhalationsnarkose ist keine nebenwirkungsarme Narkose. Alle volatilen Anästhetika sind atem- und kreislaufdepressiv. Von Vorteil ist jedoch, dass die atemdepressive und blutdrucksenkende Wirkung von Isofluran und Sevofluran stark dosisabhängig ist. Über eine Dosisreduktion kann deshalb eine Verringerung der Nebenwirkungen erreicht werden. Von Vorteil ist auch, dass die für einen Patienten notwendige Konzentration eines volatilen Anästhetikums nicht nur von dessen Wirkungsstärke, sondern auch von vielen anderen Faktoren abhängig ist und sich somit aktiv beeinflussen lässt.

 

  • Literatur

  • 1 Bergmann H. Randomisierte Blindstudie zur präemptiven Schmerztherapie beim Hund. [Dissertation]. Hannover: Tierärztliche Hochschule Hannover; 2003
    Search in Google Scholar
  • 2 Campagnol D, Neto FJ Teixeira, Giordano T et al. Effects of epidural administration of dexmedetomidine on the minimum alveolar concentration of isoflurane in dogs. Am J Vet Res 2007; 68: 1308-1318
    Search in Google Scholar
  • 3 Culp LB, Skarda RT, Muir WW. Comparisons of the effects of acupuncture, electroacupuncture, and transcutaneous cranial electrical stimulation on the minimum alveolar concentration of isoflurane in dogs. Am J Vet Res 2005; 66: 1364-1370
    Search in Google Scholar
  • 4 Duke T, Caulkett NA, Tataryn JM. The effect of nitrous oxide on halothane, isoflurane and sevoflurane requirements in ventilated dogs undergoing ovariohysterectomy. Vet Anaesth Analg 2006; 33: 343-350
    Search in Google Scholar
  • 5 Ewing KK, Mohammed HO, Scarlett JM et al. Reduction of isoflurane anesthetic requirement by medetomidine and its restoration by atipamezole in dogs. Am J Vet Res 1993; 54: 294-299
    Search in Google Scholar
  • 6 Heard DJ, Webb AI, Daniels RT. Effect of acepromazine on the anesthetic requirement of halothane in the dog. Am J Vet Res 1986; 47: 2113-2115
    Search in Google Scholar
  • 7 Ilkiw JE, Pascoe PJ, Tripp LD. Effects of morphine, butorphanol, buprenorphine, and U50488H on the minimum alveolar concentration of isoflurane in cats. Am J Vet Res 2002; 63: 1198-1202
    Search in Google Scholar
  • 8 Ko JC, Lange DN, Mandsager RE, Payton ME et al. Effects of butorphanol and carprofen on the minimal alveolar concentration of isoflurane in dogs. J Am Vet Med Assoc 2000; 217: 1025-1028
    Search in Google Scholar
  • 9 Ko JC, Weil AB, Inoue T. Effects of carprofen and morphine on the minimum alveolar concentration of isoflurane in dogs. J Am Anim Hosp Assoc 2009; 45: 19-23
    Search in Google Scholar
  • 10 Lerche P, Muir WW. Effect of medetomidine on respiration and minimum alveolar concentration in halothane- and isoflurane-anesthetized dogs. Am J Vet Res 2006; 67: 782-789
    Search in Google Scholar
  • 11 Matsubara LM, Oliva VNLS, Gabas GT et al. Effect of lidocaine on the minimum alveolar concentration of sevofluran in dogs. Vet Anaesth Analg 2009; 36: 407-413
    Search in Google Scholar
  • 12 Michelsen LG, Salmenperä M, Hug CC et al Anesthetic potency of remifentanil in dogs. Anesthesiology 1996; 84: 865-872
    Search in Google Scholar
  • 13 Muir WW, Wiese AJ, March PA. Effects of morphine, lidocaine, ketamine, and morphine-lidocaine-ketamine drug combination on minimum alveolar concentration in dogs anesthetized with isoflurane. Am J Vet Res 2003; 64: 1155-1160
    Search in Google Scholar
  • 14 Murphy MR, Hug CC (a). The anesthetic potency of fentanyl in terms of its reduction of enflurane MAC. Anesthesiology 1982; 57: 485-488
    Search in Google Scholar
  • 15 Murphy MR, Hug CC (b). The enflurane sparing effect of morphine, butorphanol, and nalbupine. Anesthesiology 1982; 57: 489-492
    Search in Google Scholar
  • 16 Nguyen D, Abdul-Rasool I, Ward D et al. Ventilatory effects of dexmedetomidine, atipamezole, and isoflurane in dogs. Anesthesiology 1992; 76: 573-579
    Search in Google Scholar
  • 17 Pascoe PJ, Ilkiw JE, Craig C et al. The effects of ketamin on the minimum alveolar concentration of isoflurane in cats. Vet Anaesth Analg 2007; 34: 31-39
    Search in Google Scholar
  • 18 Pypendop BH, Ilkiw JE. Assessement of the hemodynamic effects of lidocaine administered IV in isoflurane-anesthetized cats. Am J Vet Res 2005; 66: 661-668
    Search in Google Scholar
  • 19 Pypendop BH, Pascoe PJ, Ilkiw JE. Effects of epidural administration of morphine and buprenorphine on the minimum alveolar concentration of isoflurane in cats. Am J Vet Res 2006; 67: 1471-1475
    Search in Google Scholar
  • 20 Rector E, Kramer S, Kietzmann M et al. Beurteilung der antinozizeptiven Wirkung von systemisch und epidural appliziertem Xylazin in Allgemeinanästhesie mit Isofluran bei Hunden sowie Auswirkungen der Atipamezolgabe auf die postoperative Analgesie. Berl Münch Tierärztl Wschr 1998; 111: 438-451
    Search in Google Scholar
  • 21 Troncy E, Cuvelliez SG, Blais D. Evaluation of analgesia and cardiorespiratory effects of epidurally administered butorphanol in isoflurane-anesthetized dogs. Am J Vet Res 1996; 57: 478-1482
    Search in Google Scholar
  • 22 Valverde A, Doherty TJ, Hernándz J et al. Effect of lidocaine on the minimum alveolar concentration of isoflurane in dogs. Vet Anaesth Analg 2004; 31: 264-271
    Search in Google Scholar
  • 23 Valverde A, Dyson DH, McDonell WN. Epidural morphine reduces halothane MAC in the dog. Can J Anaesth 1989; 36: 629-632
    Search in Google Scholar
  • 24 Wilson D, Pettifer GR, Hosgood G. Effect of transdermally administered fentanyl on minimum alveolar concentration of isoflurane in normothermic and hypothermic dogs. J Am Vet Med Assoc 2006; 228: 1042-1046
    Search in Google Scholar
  • 25 Yackey M, Ilkiw JE, Pascoe PJ et al. Effect of transdermally administered fentanyl on minimum alveolar concentration of isoflurane in cats. Vet Anaesth Analg 2004; 31: 183-189
    Search in Google Scholar
  • 26 Yamashita K, Okano Y, Yamashita M et al. Effects of carprofen and meloxicam with or without butorphanol on the minimum alveolar concentration of sevoflurane in dogs. J Vet Med Sci 2008; 70: 29-35
    Search in Google Scholar