Multiple Sklerose

Multiple Sklerose - Neuroimmunologie - Autoimmunität - T-Zellen - Neurodegeneration - funktionelle Genetik

multiple sclerosis - neuroimmunology - autoimmunity - T cells - neurodegeneration - functional genetics

Literatur

• 1 Compston A, Coles A. Multiple sclerosis.  Lancet. 2008;  372 1502-1517
• 2 Goverman J. Autoimmune T cell responses in the central nervous system.  Nat Rev Immunol. 2009;  9 393-407
• 3 Friese M A, Jakobsen K B, Friis L. et al . Opposing effects of HLA class I molecules in tuning autoreactive CD8+ T cells in multiple sclerosis.  Nature medicine. 2008;  14 1227-1235
• 4 Waxman S G. Axonal conduction and injury in multiple sclerosis: the role of sodium channels.  Nat Rev Neurosci. 2006;  7 932-941
• 5 Friese M A, Craner M J, Etzensperger R. et al . Acid-sensing ion channel-1 contributes to axonal degeneration in autoimmune inflammation of the central nervous system.  Nature medicine. 2007;  13 1483-1489