Preoperative Embolization in Mediastinal Castleman's Disease

Abstract

Castleman's disease is a rare lymphoproliferative disease and its etiology is still unknown. It may occur at every site where lymph tissue is present. A definitive treatment is possible with complete resection. The most important problem is bleeding which may occur during surgery due to the high vascularization. In this study, we present the surgical treatment of a case with mediastinal Castleman's disease, treated preoperatively with embolization because of hypervascularization detected on thoracic CT.

Key words

Castleman's disease - embolization - thoracic surgery

References

• 1 Keller A R, Hochholzer L, Castleman B. Hyaline-vascular and plasma-cell types of giant lymph node hyperplasia of the mediastinum and other locations.  Cancer. 1972;  29 670-683
• 2 Bowne W B, Lewis J J, Filippa D A, Niesvizky R. The management of unicentric and multicentric Castleman's disease. A report of 16 cases and review of the literature.  Cancer. 1999;  85 706-717
• 3 Swee W, Housseini A M, Angle J F, Jones D R, Daniel T M, Turba U C, Abdel-Gawad E A, Hagspiel K D. Preoperative embolization of Castleman's disease using microspheres.  Ann Thorac Surg. 2009;  88 1999-2001
• 4 Kim J H, Jun T G, Sung S W et al. Giant lymph node hyperplasia (Castleman's disease) in the chest.  Ann Thorac Surg. 1995;  59 1162-1165
• 5 Yeh C M, Chou C M, Wong L C. Castleman's disease mimicking intrapulmonary malignancy.  Ann Thorac Surg. 2007;  84 e6-e7