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Semin Liver Dis 2010; 30(2): 205-209
DOI: 10.1055/s-0030-1253523
DIAGNOSTIC PROBLEMS IN HEPATOLOGY

© Thieme Medical Publishers

A Patient with Persistent Pruritus

Lawrence U. Liu1 , Lihui Qin2 , A.S. Knisely3
  • 1Division of Liver Diseases, The Mount Sinai Medical Center, New York, New York
  • 2Department of Pathology, The Mount Sinai Medical Center, New York, New York
  • 3Institute of Liver Studies/Histopathology, King's College Hospital, London, United Kingdom
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Publication History

Publication Date:
26 April 2010 (online)

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ABSTRACT

We present a patient with an initial and acute presentation of jaundice and marked persistent pruritus. Laboratory and radiology test results eliminated the possibility of acute hepatitis A/B/C viral infections, primary biliary cirrhosis, autoimmune hepatitis, Wilson disease, paraneoplastic cholestasis, and obstructive biliary disease. Centrilobular cholestasis was prominent in a liver biopsy specimen. Benign recurrent intrahepatic cholestasis (BRIC) was diagnosed through a review of the clinical history, available data, and the subsequent exclusion of other possible etiologies. The patient's clinical features resolved within 3 months of medical treatment.

KEYWORDS

Recurrent pruritus - jaundice - cholestasis

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Lawrence U LiuM.D. 

Division of Liver Diseases, The Mount Sinai Medical Center

One Gustave L. Levy Place, Box 1104, New York, NY 10029

Email: Lawrence.Liu@mountsinai.org