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Synthesis 2010(16): 2767-2770  
DOI: 10.1055/s-0030-1258139
PAPER
© Georg Thieme Verlag Stuttgart ˙ New York

An Efficient Synthesis of Fused 3-Formylpyridines and 5-Formylpyrimidines

Andrey P. Mityuka, Sergey E. Kolodychb, Sergey A. Mytnykb, Yuri V. Dmytrivb, Dmitriy M. Volochnyuka, Pavel K. Mykhailiuk*a,b, Andrey A. Tolmacheva,b
a Enamine Ltd., Oleksandra Matrosova Street 23, Kiev 01103, Ukraine
Fax: +380(44)2351273; e-Mail: Pashamk@gmx.de;
b Department of Chemistry, Kiev National Taras Shevchenko University, Volodymyrska Street 64, Kiev 01033, Ukraine
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Publication History

Received 13 April 2010
Publication Date:
01 July 2010 (online)

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Abstract

Cyclization of 2-dimethylaminomethylene-1,3-bis(di­methylimonio)propane diperchlorate with various amino heterocycles led to the formation of a series of fused heterocyclic systems containing a 3-formylpyridine or 5-formylpyrimidine unit.

Key words

fused pyridines - fused pyrimidines - cyclization reactions - amino heterocycles - 2-dimethylaminomethylene-1,3-bis(dimethylimonio)propane diperchlorate

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