Subscribe to RSS
Please copy the URL and add it into your RSS Feed Reader.
https://www.thieme-connect.de/rss/thieme/en/10.1055-s-00000083.xml
Synlett 2011(17): 2482-2486
DOI: 10.1055/s-0030-1260318
DOI: 10.1055/s-0030-1260318
LETTER
© Georg Thieme Verlag
Stuttgart ˙ New York
Synthesis of Ten Members of the Maradolipid Family; Novel Diacyltrehalose Glycolipids from Caenorhabditis elegans
Further Information
Received
25 July 2011
Publication Date:
19 September 2011 (online)
Publication History
Publication Date:
19 September 2011 (online)
![](https://www.thieme-connect.de/media/synlett/201117/lookinside/thumbnails/10.1055-s-0030-1260318-1.jpg)
Abstract
The synthesis of ten members of the maradolipid family is described using a direct route starting from trehalose.
Key words
acylation - carbohydrates - lipids - natural products - regioselectivity
- Supporting Information for this article is available online:
- Supporting Information
- 1
Antebi A.Culotti JG.Hedgecock EM. Development 1998, 125: 1191 -
2a
Maytash V.Entchev EV.Mende F.Wilsch-Bräuninger M.Thiele C.Schmidt AW.Knölker H.-J.Ward S.Kurzchalia TV. PloS Biol. 2004, 2: 1561 -
2b
Martin R.Schmidt AW.Theumer G.Krause T.Entchev EV.Kurzchalia TV.Knölker H.-J. Org. Biomol. Chem. 2009, 7: 909 -
2c
Hannich JT.Entchev EV.Mende F.Boytchev H.Martin R.Zagoriy V.Theumer G.Riezmann I.Riezmann H.Knölker H.-J.Kurzchalia TV. Dev. Cell 2009, 16: 833 -
2d
Martin R.Entchev EV.Däbritz F.Kurzchalia TV.Knölker H.-J. Eur. J. Org. Chem. 2009, 3703 -
2e For a review, see:
Martin R.Entchev EV.Kurzchalia TV.Knölker H.-J. Org. Biomol. Chem. 2010, 8: 739 - 3
Penkov S.Mende F.Zagoriy V.Erkut C.Martin R.Pässler U.Schuhmann K.Schwudke D.Gruner M.Mäntler J.Reichert-Müller T.Shevchenko A.Knölker H.-J.Kurzchalia TV. Angew. Chem. Int. Ed. 2010, 49: 9430 ; Angew. Chem. 2010, 122: 9620 - 4
Noll H.Bloch H.Asselineau J.Lederer E. Biochim. Biophys. Acta 1956, 20: 299 - 5
Johnson DA. Carbohydr. Res. 1992, 237: 313 - 6
Datta AK.Takayama K.Nashed MA.Anderson L. Carbohydr. Res. 1991, 218: 95 - 7
Charette AB.Francoeur S.Martel J.Wib N. Angew. Chem. Int. Ed. 2000, 39: 4539 ; Angew. Chem. 2000, 112, 4713