Synthesis of α-C-Glycosides by Samarium Diiodide Mediated
Coupling of Glycosyl Pyridyl Sulfones with Alkenes

Gen Li; De-Cai Xiong; Xin-Shan Ye

doi:10.1055/s-0030-1261230

LETTER

Synthesis of α-C-Glycosides by Samarium Diiodide Mediated Coupling of Glycosyl Pyridyl Sulfones with Alkenes

Gen Li, De-Cai Xiong, Xin-Shan Ye*
State Key Laboratory of Natural and Biomimetic Drugs and School of Pharmaceutical Sciences, Peking University, Xue Yuan Road 38, Beijing 100191, P. R. of China
Fax: +86(10)82802724; e-Mail: xinshan@bjmu.edu.cn;

Abstract

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Abstract

A mild method for the synthesis of α-C-glycosides by the samarium diiodide mediated coupling reactions of glycosyl 2-pyridyl sulfones with different α,β-unsaturated carbonyl compounds has been developed. This method allows the use of less amount of substrates.

Key words

C-glycosides - samarium diiodide - glycosyl 2-pyridyl sulfones - coupling reaction

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