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Thorac Cardiovasc Surg 2012; 60(06): 421-424
DOI: 10.1055/s-0030-1271043
DOI: 10.1055/s-0030-1271043
Case Reports
Sentinel Node Microscopic Metastasis Detected after Segmentectomy for Lung Cancer Followed by Completion Lobectomy: Two Case Reports
Further Information
Publication History
03 February 2011
25 February 2011
14 March 2011
Publication Date:
12 May 2011 (online)
Abstract
We performed sentinel node identification using radioisotopic and/or dye techniques to determine the final indication after segmentectomy in cases with non-small cell lung cancer. Sentinel nodes were examined using intraoperative frozen sections stained with hematoxylin and eosin. We present 2 cases with completion lobectomy performed 7 and 11 days after segmentectomy because immunohistochemical staining of the sentinel nodes showed the presence of microscopic metastases that were not detected by the examination of intraoperative frozen sections.
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References
- 1 Okada M, Koike T, Higashiyama M, Yamato Y, Kodama K, Tsubota N. Radical sublobar resection for small-sized non-small cell lung cancer: a multicenter study. J Thorac Cardiovasc Surg 2006; 132 (4) 769-775
- 2 Nomori H, Ikeda K, Mori T , et al. Sentinel node navigation segmentectomy for clinical stage IA non-small cell lung cancer. J Thorac Cardiovasc Surg 2007; 133 (3) 780-785
- 3 Nomori H, Watanabe K, Ohtsuka T, Naruke T, Suemasu K. In vivo identification of sentinel lymph nodes for clinical stage I non-small cell lung cancer for abbreviation of mediastinal lymph node dissection. Lung Cancer 2004; 46 (1) 49-55
- 4 Yamashita S, Tokuishi K, Anami K , et al. Video-assisted thoracoscopic indocyanine green fluorescence imaging system shows sentinel lymph nodes in non-small-cell lung cancer. J Thorac Cardiovasc Surg 2011; 141 (1) 141-144
- 5 Tezel C, Ersev AA, Kiral H , et al. The impact of immunohistochemical detection of positive lymph nodes in early stage lung cancer. Thorac Cardiovasc Surg 2006; 54 (2) 124-128
- 6 Osaki T, Oyama T, Gu CD , et al. Prognostic impact of micrometastatic tumor cells in the lymph nodes and bone marrow of patients with completely resected stage I non-small-cell lung cancer. J Clin Oncol 2002; 20: 2930-2936
- 7 The Japan Lung Cancer Society.. General Rule for Clinical and Pathological Record of Lung Cancer. 7th ed. Tokyo:: Kanehara; 2010: 91-92
- 8 Nicholson AG, Graham AN, Pezzella F, Angeta G, Goldstraw P, Pastorino U. Does the use of immunohistochemistry to identify micrometastases provide useful information in the staging of node negative non-small cell lung cancer?. Lung Cancer 1997; 18: 231-240
- 9 Marchevsky AM, Qiao JH, Krajisnik S, Mirocha JM, McKenna RJ. The prognostic significance of intranodal isolated tumor cells and micrometastases in patients with non-small cell carcinoma of the lung. J Thorac Cardiovasc Surg 2003; 126 (2) 551-557