Subscribe to RSS
DOI: 10.1055/s-0031-1275605
© Georg Thieme Verlag Stuttgart · New York
Biokompatibilität dentaler Komposite
Publication History
Publication Date:
18 March 2011 (online)
Lernziele
Der Leser sollte nach dem Durcharbeiten des Artikels
-
die Hauptkomponenten dentaler Komposite und Dentinadhäsive kennen,
-
Gründe für die Relevanz der Analyse der Biokompatibilität dentaler Komposite benennen,
-
die biologische Wirkung dentaler Monomere in vivo diskutieren können,
-
die Relevanz von oxidativem Stress für zytotoxische Effekte dentaler Monomere verstehen und
-
Grundzüge der möglichen Wirkung dentaler Monomere auf die Physiologie von Zellen des Dentin-Pulpa-Komplexes skizzieren können.
Literatur
- 1 Dauvillier BS, Aarnts MP, Feilzer AJ. Developments in shrinkage control of adhesive restoratives. J Esthet Dent. 2000; 12 291-299
- 2 Demirci M, Hiller KA, Bosl C et al.. The induction of oxidative stress, cytotoxicity, and genotoxicity by dental adhesives. Dent Mater. 2008; 24 362-371
- 3 Durner J, Kreppel H, Zaspel J et al.. The toxicokinetics and distribution of 2-hydroxyethyl methacrylate in mice. Biomaterials. 2009; 30 2066-2071
- 4 Durner J, Spahl W, Zaspel J et al.. Eluted substances from unpolymerized and polymerized dental restorative materials and their Nernst partition coefficient. Dent Mater. 2010; 26 91-99
- 5 Eick JD, Byerley TJ, Chappell RP et al.. Properties of expanding SOC/epoxy copolymers for dental use in dental composites. Dent Mater. 1993; 9 123-127
- 6 Ferracane JL, Cooper PR, Smith AJ. Can interaction of materials with the dentin-pulp complex contribute to dentin regeneration?. Odontology. 2010; 98 2-14
- 7 Ferracane JL. Developing a more complete understanding of stresses produced in dental composites during polymerization. Dent Mater. 2005; 21 36-42
- 8 Ferracane JL. Resin composite-State of the art. Dent Mater. DOI: 10.1016/j.dental 2010; 10 020
- 9 Fleisch AF, Sheffield PE, Chinn C et al.. Bisphenol A and related compounds in dental materials. Pediatrics. 2010; 126 760-768
- 10 Freidig A, Hofhuis M, Van Holstijn I et al.. Glutathione depletion in rat hepatocytes: a mixture toxicity study with alpha, beta-unsaturated esters. Xenobiotica. 2001; 31 295-307
- 11 Galler KM, Schweikl H, Hiller KA et al.. TEGDMA reduces mineralization in dental pulp cells. J Dent Res. DOI: 10.1177/0022034510384618 [Epub ahead of print] 2010;
- 12 Geukens S, Goossens A. Occupational contact allergy to (meth)acrylates. Contact Dermatitis. 2001; 44 153-159
- 13 Geurtsen W, Leyhausen G. Chemical-biological interactions of the resin monomer triethyleneglycol-dimethacrylate (TEGDMA). J Dent Res. 2001; 80 2046-2050
- 14 Goldberg M, Smith AJ. Cells and extracellular matrices of dentin and pulp: a biological basis for repair and tissue engineering. Crit Rev Oral Biol Med. 2004; 15 13-27
- 15 Hanks CT, Strawn SE, Wataha JC et al.. Cytotoxic effects of resin components on cultured mammalian fibroblasts. J Dent Res. 1991; 70 1450-1455
- 16 Ilie N, Hickel R. Macro-, micro- and nano-mechanical investigations on silorane and methacrylate-based composites. Dent Mater. 2009; 25 810-819
- 17 Kermanshahi S, Santerre JP, Cvitkovitch et al.. Biodegradation of resin-dentin interfaces increases bacterial microleakage. J Dent Res. 2010; 89 996-1001
- 18 Krifka S, Seidenader C, Hiller KA et al.. The generation of oxidative stress and cytotoxicity by modern dental composites. Clin Oral Invest 2011. [Epub ahead of print]
- 19 Marquardt W, Seiss M, Hickel R et al.. Volatile methacrylates in dental practices. J Adhes Dent. 2009; 11 101-107
- 20 Michelsen VB, Moe G, Strøm MB et al.. Quantitative analysis of TEGDMA and HEMA eluted into saliva from two dental composites by use of GC/MS and tailor-made internal standards. Dent Mater. 2008; 24 724-731
- 21 Noda M, Wataha JC, Kaga M et al.. Components of dentinal adhesives modulate heat shock protein 72 expression in heat-stressed THP-1 human monocytes at sublethal concentrations. J Dent Res. 2002; 81 265-269
- 22 Peutzfeldt A. Resin composites in dentistry: the monomer systems. Eur J Oral Sci. 1997; 105 97-116
- 23 Qin C, Baba O, Butler WT. Post-translational modifications of sibling proteins and their roles in osteogenesis and dentinogenesis. Crit Rev Oral Biol Med. 2004; 15 126-136
- 24 Reichl FX, Durner J, Hickel R et al.. Uptake, clearance and metabolism of TEGDMA in guinea pigs. Dent Mater. 2002; 18 581-589
- 25 Reichl FX, Seiss M, Buters J et al.. Expression of CYP450-2E1 and formation of 2,3-epoxymethacrylic acid (2,3-EMA) in human oral cells exposed to dental materials. Dent Mater. 2010; 26 1151-1156
- 26 Samuelsen JT, Kopperud HM, Holme JA et al.. Role of thiol-complex formation in 2-hydroxyethyl- methacrylate-induced toxicity in vitro. J Biomed Mater Res A. 2011; 96 395-401
- 27 Schmalz G. Komposit-Kunststoffe. In: Schmalz G, Arenholt-Bindslev D, (Hrsg.) Biokompatibilität zahnärztlicher Werkstoffe. München: Elsevier-Urban & Fischer; 2005: 99-132
- 28 Schweikl H, Schmalz G. Triethylene glycol dimethacrylate induces large deletions in the hprt gene in V79 cells. Mutation Res. 1999; 438 71-78
- 29 Schweikl H, Spagnuolo G, Schmalz G. Genetic and cellular toxicology of dental resin monomers. J Dent Res. 2006; 85 870-877
- 30 Smith AJ, Cassidy N, Perry H et al.. Reactionary dentinogenesis. Int J Dev Biol. 1995; 39 273-280
- 31 Technische Regeln für Gefahrstoffe (TRGS). TRGS 900 – Arbeitsplatzgrenzwerte. Im Internet: http://www.umwelt-online.de/regelwerk/t_regeln/trgs/trgs900/mak_ges.htm Stand Januar/2006
- 32 Watson WH, Chen Y, Jones DP. Redox state of glutathione and thioredoxin in differentiation and apoptosis. Biofactors. 2003; 17 307-314
- 33 Weinmann W, Thalacker C, Guggenberger R. Siloranes in dental composites. Dent Mater. 2005; 21 68-74
- 34 Yoshii E. Cytotoxic effects of acrylates and methacrylates: relationships of monomer structures and cytotoxicity. J Biomed Mater Res. 1997; 37 517-524
Korrespondenzadresse
Prof. Helmut Schweikl
Poliklinik für Zahnerhaltung und Parodontologie Universitätsklinikum Regensburg
Franz-Josef-Strauss-Allee 11
93042 Regensburg
Email: helmut.schweikl@klinik.uni-regensburg.de