Planta Med 2012; 78(1): 39-45
DOI: 10.1055/s-0031-1280266
Natural Product Chemistry
Original Papers
© Georg Thieme Verlag KG Stuttgart · New York

Compounds from Arnebia euchroma and Their Related Anti-HCV and Antibacterial Activities

Hong-Mei Li1 , Ying-Lei Tang1 , Zhong-Hua Zhang1 , Chen-Jian Liu1 , Hai-Zhou Li1 , Rong-Tao Li1 , Xue-Shan Xia1
  • 1The College of Life Science and Technology, Kunming University of Science and Technology, Kunming, Yunnan, P. R. China
Further Information

Publication History

received June 1, 2011 revised Sept. 1, 2011

accepted Sept. 5, 2011

Publication Date:
07 October 2011 (online)

Preview

Abstract

Three new hydroquinone terpenoids with benzogeijerene skeletons, euchroquinols A–C (13), and a new monoterpenylbenzenoid, 9,17-epoxyarnebinol (4), along with five known compounds were isolated from the stem bark of Arnebia euchroma. Shikonin (6) exhibited potent anti-HCV activity with a selective index of 43.56, and compounds 1, 6, and des-O-methyllasiodiplodin (7) showed anti-Staphylococcus aureus activity with MICs of 0.5, 0.125, and 0.125 mg/mL, respectively.

References

Prof. Rong-Tao Li

College of Life Science and Technology
Kunming University of Science and Technology

Kunming 650224, Yunnan

P. R. China

Phone: +86 871 5 10 38 45

Fax: +86 871 3 80 19 56

Email: rongtaolikm@yahoo.cn

Prof. Xue-Shan Xia

College of Life Science and Technology
Kunming University of Science and Technology

Kunming 650224, Yunnan

P. R. China

Phone: +86 871 5 10 38 45

Fax: +86 871 3 80 19 56

Email: oliverxia2000@yahoo.com.cn