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DOI: 10.1055/s-0031-1286630
Einfluss von Mikronährstoffen auf Mundgesundheit und Allgemeinbefinden
The Influence of Micronutrients on oral and General HealthPublication History
Publication Date:
23 August 2011 (online)
![](https://www.thieme-connect.de/media/zwr/20110708/lookinside/thumbnails/10.1055-s-0031-1286630-1.jpg)
In der vorliegenden klinischen Studie sollte der Einfluss einer Mikronährstoffkombination bei Personen unter hoher Stressbelastung untersucht werden. Für diese Studie wurden 42 gesunde Studenten (30 Frauen, 12 Männer) mit einem Durchschnittsalter von 27 Jahren ausgewählt, die alle unter hohen Prüfungsbelastungen standen. Nach dem positiven Votum der Ethikkommission wurde einer Studentengruppe (n = 21) über einen Zeitraum von 3 Monaten die Mikronährstoffkombination zugewiesen, die anderen Studenten (n = 21 Personen) dienten als Kontrollgruppe. Bei allen Probanden wurden zu Beginn und nach Abschluss der Studie eine zahnärztliche Untersuchung, die Bestimmung von 10 parodontalpathogenen Keimen, eine Speichelanalyse sowie eine Blutanalyse durchgeführt. Zusätzlich füllten alle Probanden einen Fragebogen zur Ernährung, Lebensqualität und Stressbelastung aus. Die Auswertung der Untersuchung zeigte, dass bei allen Probanden nach Abschluss der Studie (n = 39) eine leichte Verschlechterung der Mundhygiene und vermehrt ungesunde Ernährung zu verzeichnen war. Die Einnahme der Mikronährstoffe führte im Vergleich zur Kontrollgruppe zu einer leichten Verbesserung des Entzündungsgrades der Gingiva. In der Blutanalyse zeigte sich eine Verbesserung der Vitaminkonzentrationen (VitC, VitE), der Zinkkonzentration und des Wertes von c-reaktivem Protein. In weiteren Studien sollte jedoch eine größere Zahl an Personen mit zusätzlichem Vorliegen von parodontalen Erkrankungen untersucht werden, um den Einfluss einer Mikronährstoffsupplementierung deutlicher belegen zu können.
The aim of the present clinical study was to examine the influence of a combination of micronutrients on individuals with high stress experience. 42 healthy students (30 female, 12 male) with an average age of 27 years, experiencing high examination stress were chosen. After approval by the ethics commission, one group of students (n = 21) took a combination of micronutrients, whereas other students (n = 21) served as control group. All participants underwent at the beginning and at the end of the trial a dental examination, a determination of 10 periodontal pathogens, a salivary and a blood analysis. In addition, the participants filled in a questionnaire on nutrition, quality of life and degree of stress experience. The evaluation of the results, obtained at the end of the trial period, showed that for all students (n = 39) a slight worsening of oral hygiene and an increased consumption of unhealthy food could be observed. The intake of the micronutrients leads to a slight improvement of the degree of gingival inflammation in comparison to the control group. The blood analysis showed an increase in the vitamin (vitamin C, vitamin E) and zinc concentrations, and of the CRP status. However, additional studies are necessary to investigate a higher number of subjects, also suffering from periodontal disease, to show more clearly the effect of a micronutrient supplementation.
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