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Synthesis 2012(5): 711-716  
DOI: 10.1055/s-0031-1289698
PAPER
© Georg Thieme Verlag Stuttgart ˙ New York

N-Heterocyclic Carbene-Palladium(II)-1-Methylimidazole Complex Catalyzed α-Arylation of Ketones with Aryl Chlorides

Zheng-Kang Xiao, Li-Xiong Shao*
College of Chemistry and Materials Engineering, Wenzhou University, Chashan University Town, Wenzhou, Zhejiang Province 325035, P. R. of China
Fax: +86(577)86689300; e-Mail: Shaolix@wzu.edu.cn;
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Publication History

Received 12 November 2011
Publication Date:
10 February 2012 (online)

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Abstract

An easily available NHC-Pd(II)-Im (NHC = N-heterocyclic carbene, Im = 1-methylimidazole) complex was found to be an efficient catalyst for the α-arylation reaction between ketones and aryl chlorides. Under the optimal conditions, all reactions proceeded smoothly to give the desired products in good to high yields within hours.

Key words

N-heterocyclic carbenes - palladium - α-arylation - aryl chlorides - ketones

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