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Synthesis 2012(3): 377-379  
DOI: 10.1055/s-0031-1289994
SHORTPAPER
© Georg Thieme Verlag Stuttgart ˙ New York

A Thiophosphoryl Chloride Assisted Transformation of Arylaldoximes to Thioamides

Lokesh Kumar Pandey, Uma Pathak*, Sweta Mathur, M. V. S. Suryanarayana
Synthetic Chemistry Division, Defence Research & Development Establishment, Gwalior (MP) 474 002, India
Fax: +91(751)2341148; e-Mail: sc_drde@rediffmail.com;
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Publication History

Received 24 October 2011
Publication Date:
22 December 2011 (online)

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Abstract

Primary benzothioamides were accessed from benzaldoximes (benzaldehyde oximes) via benzonitriles in a sequential tandem approach utilizing thiophosphoryl chloride as a dehydrating and thionating agent.

Key words

primary thioamides - oximes - thiophosphoryl chloride - nitriles

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