DMW – Klinischer Fortschritt, Table of Contents Dtsch Med Wochenschr 2011; 136(48): 2466-2469DOI: 10.1055/s-0031-1297268 Hämatologie und Onkologie | Commentary Hämatologie © Georg Thieme Verlag KG Stuttgart · New York Akute lymphatische Leukämie des Erwachsenen Acute lymphoblastic leukemia in the adultN. Gökbuget1 1Medizinische Klinik II, Johann Wolfgang Goethe-Universität Frankfurt Recommend Article Abstract Buy Article Schlüsselwörter Akute lymphatische Leukämie Keywords acute lymphoblastic Full Text References Literatur 1 Bassan R, Hoelzer D. Modern therapy of acute lymphoblastic leukemia. J Clin Oncol. 2011; 29 532-543 2 Bruggemann M, Schrauder A, Raff T. et al . Standardized MRD quantification in European ALL trials: proceedings of the Second International Symposium on MRD assessment in Kiel, Germany, 18 – 20 September 2008. Leukemia. 2010; 24 521-535 3 Campana D. Progress of minimal residual disease studies in childhood acute leukemia. Curr Hematol Malig Rep. 2010; 5 169-176 4 Diller L. Clinical practice. Adult primary care after childhood acute lymphoblastic leukemia. New Engl J Med. 2011; 365 1417-1424 5 Foa R, Vitale A, Vignetti M. et al . Dasatinib as first-line treatment for adult patients with Philadelphia chromosome-positive acute lymphoblastic leukemia. Blood. 2011; Sep. 19 [Epub ahead of print] 6 Gökbuget N, Basara N, Baurmann H. et al . High single drug activity of nelarabine in relapsed T-lymphoblastic leukemia/lymphoma offers curative option with subsequent stem cell transplantation. Blood. 2011; 118 3504-3511 7 Gökbuget N. Acute lymphoblastic leukemia in older patients. Hematology Education (Education Programme for the 16th Congress of the EHA). 2011; 20-26 8 Gökbuget N. Recommendations of the European Working Group for Adult ALL. Bremen: UNI-MED; 2011 9 Gökbuget N. Salvage therapy of adult acute lymphoblastic leukemia. In: Faderl S, Kantarjian H Leukemias: Principles and Practice of Therapy. Oxford; Blackwell; 2011: 217-227 10 Oliansky D M, Larson R A, Weisdorf D. et al . The role of cytotoxic therapy with hematopoietic stem cell transplantation in the treatment of adult acute lymphoblastic leukemia: Update of the 2006 evidence-based review. Biol Blood Marrow Transplant. 2011; Jul. 29 [Epub ahead of print] 11 Ottmann O G, Pfeifer H. Management of Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL). Hematology Am Soc Hematol Educ Program. 2009; 371-2381 12 Stock W, Douer D, Deangelo D J. et al . Prevention and management of asparaginase/pegasparaginase-associated toxicities in adults and older adolescents: recommendations of an expert panel. Leuk Lymphoma. 2011; Aug. 10 [Epub ahead of print] 13 Topp M S, Kufer P, Gökbuget N. et al . Targeted therapy with the T-cell-engaging antibody blinatumomab of chemotherapy-refractory minimal residual disease in B-lineage acute lymphoblastic leukemia patients results in high response rate and prolonged leukemia-free survival. J Clin Oncol. 2011; 29 2493-2498 Dr. Nicola Gökbuget Medizinische Klinik IIJohann Wolfgang Goethe-Universität Theodor-Stern-Kai 7 60590 Frankfurt Phone: 069/6301-6364 Fax: 069/6301-7463 Email: goekbuget@em.uni-frankfurt.de