Antimicrobial Constituents from the Tubers of Bletilla ochracea

Abstract

A new 2-(2-methylpropyl)butanedioic acid derivative, bletillin A (1), and a new bibenzyl, bletillin B (2), together with seventeen known compounds (3–19), were isolated from the tubers of Bletilla ochracea Schltr. Their structures were established by detailed spectroscopic analyses. Phenanthrenes (12–14) exhibited antibacterial activities against gram-positive bacteria Staphylococcus aureus, S. epidermidis, and Bacillus subtilis, with MIC values of 12.5–25 µg/mL.

Key words

Bletilla ochracea - Orchidaceae - 2-(2-methylpropyl)butanedioic acid derivatives - phenanthrene - bibenzyl - antibacterial activity

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