Correlation Between the Severity of Neurological Deficits in Patients with Symptomatic Spinal Metastases and Short-Term Postoperative Functional Neurological Improvements

C. Hessler; J. Madert; O. Heese

doi:10.1055/s-0032-1304499

Journal of Neurological Surgery Part A: Central European Neurosurgery, Table of Contents

J Neurol Surg A Cent Eur Neurosurg 2012; 73(01): 05-09
DOI: 10.1055/s-0032-1304499

Original Article

Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Correlation Between the Severity of Neurological Deficits in Patients with Symptomatic Spinal Metastases and Short-Term Postoperative Functional Neurological Improvements^[*]

C. Hessler

¹University Hospital Hamburg-Eppendorf, Neurosurgery, Hamburg, Germany

,

J. Madert

²Asklepios Hospital Hamburg St. Georg, Traumatology, Hamburg, Germany

,

O. Heese

¹University Hospital Hamburg-Eppendorf, Neurosurgery, Hamburg, Germany

› Author Affiliations

Abstract

Objective The correlation between the severity of neurological deficit of patients with symptomatic spinal metastases and short-term, postoperative, functional improvements after surgery is unclear. The aim of this clinical trial was to determine the influence of neurological deficit severity on short-term functional outcomes after surgery, and to devise optimal treatment strategies for this patient population.

Methods Between 01/1999 and 12/2004, 194 patients with symptomatic spinal metastases were surgically treated. Each patient underwent neurological examination pre- and postoperatively. The results were ranked according to the Frankel score. The pre- and postoperative Frankel score was compared in order to assess the development of neurostatus following a surgical procedure.

Results Complete postoperative remission was seen in 27% of all patients (27/101) with a preoperative Frankel score D, as well as in 5% of all patients (4/77) with a preoperative Frankel score C. Improvement of the preoperative neurologic deficits occurred in 27% of all patients (27/101) with a preoperative Frankel score D, 58% of all patients (45/77) with a preoperative Frankel score C, 36% of all patients (5/14) with a preoperative Frankel score B, and 50% of all patients (1/2) with a preoperative Frankel score A.

Conclusion Surgical treatment of patients suffering from neurological deficits caused by spinal metastases results in neurological function improvements. The probability of neurological improvement does not correlate with the severity of the preoperative neurologic deficit. As a consequence, the decision to operate on these patients should not depend on the severity of pre-operative neurological symptoms alone.

Keywords

metastases - surgery - neurological outcome - spine

Full Text

References

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Correlation Between the Severity of Neurological Deficits in Patients with Symptomatic Spinal Metastases and Short-Term Postoperative Functional Neurological Improvements[*]

Correlation Between the Severity of Neurological Deficits in Patients with Symptomatic Spinal Metastases and Short-Term Postoperative Functional Neurological Improvements^[*]