A 23-year-old woman attended our hospital with the complaint of progressive dysphagia over the past year, especially to solid foods. Upper endoscopy showed a bulging lesion, which was probably due to external pressure on the distal part of the esophagus ([Fig. 1]). Endoscopic ultrasound (EUS) revealed a 3 × 3 cm cystic lesion in the same region, suggestive of a duplication or bronchogenic cyst ([Fig. 2]). Thoracic computed tomography showed a cystic lesion located in the same region ([Fig. 3]).
Fig. 1 Upper endoscopy in a 23-year-old woman with progressive dysphagia over the past year, showing a large bulging lesion in the lower third of the esophagus, 30 cm from the incisors.
Fig. 2 a, b Endoscopic ultrasound of the esophagus showing a large cystic lesion, 30 – 35 cm from incisors.
Fig. 3 CT scan of the thorax showing a cystic mass located in the distal part of the esophagus.
Thoracotomy was carried out and a cystic mass was found between the mucosa and muscular layers of the esophagus, and was completely resected. Pathologic examination revealed respiratory ciliated pseudostratified columnar epithelium overlying smooth muscle in the lining of the cyst wall, compatible with esophageal bronchogenic cyst ([Fig. 4]). The patient was asymptomatic on follow-up.
Fig. 4 Microscopic section showing the lining of the cyst wall: note the respiratory ciliated pseudostratified columnar epithelium and smooth muscle.
Foregut cysts are a rare developmental anomaly and believed to result from abnormal budding or division of the primitive foregut during development [1]. Bronchogenic cysts are uncommon in adults [1] and the paraesophageal type is rare [2]. In 1948, Maier divided bronchogenic cysts of the mediastinum into the following groups: paratracheal; carinal; hilar; paraesophageal; and miscellaneous [3]. Esophageal bronchogenic cysts predominately affect young women [2], as in our patient. Most patients are asymptomatic although manifestations include dysphagia, chest pain, epigastric pain, cough, and dyspnea [1]. Our patient, however, only had dysphagia. It is difficult to diagnose an intramural esophageal cyst by imaging or even on histological examination [1]. On endoscopy or barium studies, the cysts appear as a protruding submucosal mass. EUS is increasingly used to diagnose mediastinal and esophageal cysts [4]
[5]. Bronchogenic cysts should be surgically resected because surgery can be more complicated and hazardous when the cyst is symptomatic [2]. Further advances in EUS may aid in reaching a definite diagnosis before surgery.
Endoscopy_UCTN_Code_CCL_1AF_2AB
