Synlett 2013; 24(4): 499-501
DOI: 10.1055/s-0032-1318197
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© Georg Thieme Verlag Stuttgart · New York

A Mild and Highly Efficient Conversion of Arylboronic Acids into Phenols by Oxidation with MCPBA

Dong-Song Chen
School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou, Guangdong 510640, P. R. of China   Fax: +86(20)87110622   Email: chehjm@scut.edu.cn
,
Jing-Mei Huang*
School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou, Guangdong 510640, P. R. of China   Fax: +86(20)87110622   Email: chehjm@scut.edu.cn
› Author Affiliations
Further Information

Publication History

Received: 05 December 2012

Accepted after revision: 17 January 2013

Publication Date:
06 February 2013 (online)


Abstract

A mild and highly efficient synthesis of phenols from arylboronic acids in a H2O–EtOH (1:2) solution was achieved by using MCPBA as the oxidant at room temperature. Isotopical labeling studies had shown that the hydroxyl oxygen atom of the phenol might originate from the MCPBA.

Supporting Information