Synlett 2013; 24(6): 770-772
DOI: 10.1055/s-0032-1318453
letter
© Georg Thieme Verlag Stuttgart · New York

A Concise Synthesis of 4-Vinylphencyphos

Maarten W. van der Meijden
a   Syncom BV, Kadijk 3, 9747 AT Groningen, The Netherlands   Fax: +31(50)5757399   Email: r.m.kellogg@syncom.nl
,
Klaus Wurst
b   Institut für Allgemeine Anorganische und Theoretische Chemie, Universität Innsbruck, Innrain 80/82, 6020 Innsbruck, Austria
,
Richard M. Kellogg*
a   Syncom BV, Kadijk 3, 9747 AT Groningen, The Netherlands   Fax: +31(50)5757399   Email: r.m.kellogg@syncom.nl
› Author Affiliations
Further Information

Publication History

Received: 10 January 2013

Accepted after revision: 21 February 2013

Publication Date:
06 March 2013 (online)


Abstract

A fast and clean procedure has been found to prepare the 4-vinyl derivative of enantiomerically pure 2-hydroxy-5,5-dimethyl-4-phenyl-1,3,2-dioxaphosphinan-2-oxide, commonly known as phencyphos. This cyclic phosphoric acid is a popular acidic resolving agent. Functionalization opens a route to attachment to surfaces.

Supporting Information