Innere Medizin up2date 2013; 01(01): 39-54
DOI: 10.1055/s-0032-1326382
Immunsystem, Stütz- und Bindegewebe
© Georg Thieme Verlag KG Stuttgart · New York

Rehabilitation von Patienten mit rheumatoider Arthritis

Rehabilitation of patients with rheumatoid arthritis
Katharina Kerschan-Schindl
,
Klaus Machold
Further Information

Publication History

Publication Date:
09 April 2013 (online)

Abstract

Rheumatoid arthritis (RA) is a chronic inflammatory disease characterised by joint swelling, joint tenderness and joint destruction, leading to severe disability and premature mortality. RA is considered an autoimmune disease, however, lifestyle factors also influence the clinical manifestation of the disease. The ACR- (American College of Rheumatology) classification criteria have a significant limitation in discriminating patients suffering of early RA. To be able to treat these patients as soon as possible, the new ACR/EULAR- (European League Against Rheumatism-) classification criteria were developed. Despite medical treatment RA-patients often have deficits in body structure and function, activities, and participation. The international classification of functioning, disability and health (ICF) comprehensive core set for rheumatoid arthritis helps to assess patients’ daily functioning and to plan a complex rehabilitation performed by a multidisciplinary team. Non-pharmacologic therapeutic options include exercise, occupational therapy, different physical modalities, psychologic care, and special diets. Such a rehabilitation program has to be individualised to optimise the effect and to conserve the patient’s function and independance as long as possible.

Kernaussagen
  • Die rheumatoide Arthritis ist die häufigste entzündliche Gelenkerkrankung des Erwachsenenalters, Sie ist gekennzeichnet durch die Kardinalsymptome Schwellung und Schmerz und kann mit einer Bewegungseinschränkung einhergehen.

  • Wesentlich ist die frühe Diagnostik und das Einleiten einer sachgemäßen Pharmakotherapie, welche das Fortschreiten der Erkrankung verhindert oder verzögert.

  • Die Prävention (Sekundär- und Tertiärprävention) und Rehabilitation zielen auf die Erhaltung und Wiederherstellung eines optimalen funktionalen Gesundheitszustandes bei diesen Patienten ab.

  • Das Assessment entsprechend den Core-Items des ICF ist dabei ein wichtiger Bestandteil des Rehabilitationprozesses und soll in regelmäßigen Abständen wiederholt werden.

  • Unter den präventiven und rehabilitativen Interventionen für Patienten mit RA gibt es für die Trainingstherapie eindeutige Evidenz für deren Wirksamkeit. Durch regelmäßiges gezieltes Training lassen sich Ausdauer, Kraft und Funktion der Betroffenen verbessern ohne negative Effekte auf die Gelenke zu haben.

  • Es besteht auch eindeutige Evidenz zugunsten der Wirksamkeit der Gelenkschutzinstruktion. Verschiedenen physikalisch-therapeutischen Maßnahmen wird ein zumindest kurzfristig positiver Effekt zugeschrieben, aussagekräftige Wirksamkeitsbelege bestehen jedoch kaum. Unklar ist auch ob die mediterrane Diät den Krankheitsprozess günstig zu beeinflussen vermag.

  • Eine begleitende psycholgische Unterstützung zur Bewältigung von Schmerz und Stress wirkt sich kurzfristig positiv auf das Wohlbefinden der Patienten aus.

  • Viele Interventionen, die im alltäglichen Management der RA-Patienten angewendet werden, sind trotz ihres mangelhaften Wirksamkeitsnachweis sinnvoll.

 
  • Literatur

  • 1 Lee DM, Weinblatt WE. Rheumatoid arthritis. Lancet 2001; 358: 903-911
  • 2 Myasoedova E, Crowson CS, Kremers HM et al. Is the incidence of rheumatoid arthritis rising?. Arthr Rheum 2010; 62: 1576-1582
  • 3 Scott DL, Wolfe F, Huizinga TW. Rheumatoid arthritis. Lancet 2010; 376: 1094-1108
  • 4 Kokkonen H, Söderström I, Hallmans G et al. Up-regulation of cytokines and chemokines predates the onset of rheumatoid arthritis. Arthritis Rheum 2010; 62: 383-391
  • 5 Arnett FC, Edworthy SM, Bloch DA et al. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 1988; 31: 315-24
  • 6 Van Gaalen FA, Linn-Rasker SP, van Venrooij WJ et al. Autoantibodies to cyclic citrullinated peptides predict progression to rheumatoid arthritis in patients with undifferentiated arthritis. Arthitis & Rheumatism 2004; 50: 709-715
  • 7 Aletaha D, Neogi T, Silman AJ et al. 2010 Rheumatoid arthritis classification criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative. Ann Rheum Dis 2010; 69: 1580-1588
  • 8 Prevoo MLL, van’T HoffMA, Kuper HH et al. Modified disease activity scores that include twenty-eight-point counts, development and validation in a prospective longitudinal study of patients with rheumatoid arthritis. Arthritis Rheum 1995; 38: 44-48
  • 9 Smolen JS, Breedveld FC, Schiff MH et al. A simplified disease activity index for rheumatoid arthritis for use in clinical practice. Rheumatology 2003; 42: 244-245
  • 10 Aletaha D, Smolen JS. The Simplified Disease Activity Index (SDAI) and the Clinical Disease Activity Index (CDAI): A review of their usefulness and validity in rheumatoid arthritis. Clin Exp Rheumatol 2005; 23: 100-108
  • 11 Steinbrocker O, Traeger CH, Battman RG. Therapeutic criteria in rheumatoid arthritis. J Am Med Assoc 1949; 140: 659-662
  • 12 Fries JF, Spitz PW, Young DY. The dimensions of health outcomes: the health assessment questionnaire, disability and pain scales. J Rheumatol 1982; 9: 789-793
  • 13 Ware JE, Sherboume CD. The MOS 36-item Short-Form Health Survey (SF-36). I. Conceptual framework and item selection. Med Care 1992; 30: 473-483
  • 14 Smolen JS, Landewe R, Breedveld FC et al. EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs. Annals of the Rheumatic Diseases 2010; 69: 964-975
  • 15 Hench PS, Kendall EC, Slocumb CH et al. The Effect of A Hormone of the Adrenal Cortex (17-Hydroxy-11-Dehydrocorticosterone - Compound-E) and of Pituitary Adrenocorticotrophic Hormone on Rheumatoid Arthritis – Preliminary Report. Ann Rheum Dis 1949; 8: 97-104
  • 16 Kaiser H, Kley HK. Cortisontherapie: Corticoide in Klinik und Praxis. 11. . edn. Stuttgart, New York: Thieme; 2002
  • 17 DVO-Leitlinie zur Prophylaxe, Diagnostik und Therapie der Osteoporose bei Erwachsenen. 2009 http://www.dv-osteologie.org/uploads/leitlinien/DVO-Leitlinie%202009%20Langfassung_Druck.pdf
  • 18 Stucki G, Cieza A, Geyh S et al. ICF core sets for rheumatoid arthritis. J Rehabil Med 2004; 44: 87-93
  • 19 Stamm TA, Cieza A, Coenen M et al. Validating the international classification of functioning, disability, and health comprehensive core set for rheumatoid arthritis from the patient perspective: a qualitative study. Arthritis Rheum 2005; 15: 431-439
  • 20 Uhlig T, Lillemo S, Moe RH et al. Reliability of the ICF Core Set for rheumatoid arthritis. Ann Rheum Dis 2007; 66: 1078-1094
  • 21 Sullivan PW, Ghushchyan V, Huang XY et al. Influence of rheumatoid arthritis on employment, function, and productivity in a nationally representative sample in the Unites States. J Rheumatol 2010; 37: 544-549
  • 22 Allaire S, Wolfe F, Niu J et al. Current risk factors for work disability associated with rheumatoid arthritis: recent data from a US national cohort. Arthritis Rheum 2009; 61: 321-328
  • 23 Gabriel SE, Crowson CS, Kremers HM et al. Survival in rheumatoid arthritis: a population-based analysis of trends over 40 years. Arthritis Rheum 2003; 48: 54-58
  • 24 Godha D, Shi L, Mavronicolas H. Association between tendency towards depression and severity of rheumatoid arthritis from a national representative sample: the Medical Expenditure Panel Survey. Curr Med Res Opin 2010; 26: 1685-1690
  • 25 Hagel S, Lindqvist E, Petersson IF et al. Validation of outcome measurement instruments used in a multidisciplinary rehabilitation intervention for patients with chronic inflammatory arthritis: linking to the international classification of functioning, disability and health, construct validity and responsiveness to change. J Rehabil Med 2011; 43: 411-419
  • 26 Chung KC, Burns PB, Reichert HA et al. Properties of the international classification for functioning, disability and health in assessing hand outcomes in patients with rheumatoid arthritis. J Rehabil Med 2011; 43: 292-298
  • 27 Wilcox S, Der AnanianC, Abbott J et al. Perceived exercise barriers, enablers, and benefits among exercising and nonexercising adults with arthritis: results from a quantitative study. Arthritis Rheum 2006; 55: 6161-27
  • 28 Henchoz Y, Bastardot F, Guessous I et al. Physical activity and energy expenditure in rheumatoid arthritis patients and matched controls. Rheumatology 2012; epub
  • 29 Hayashibara M, Hagino H, Katagiri H et al. Incidence and risk factors of falling in ambulatory patients with rheumatoid arthritis: a prospective 1-year study. Ost Int 2010; epub
  • 30 Van Staa TP, Geusens P, Bijlsma JW et al. Clinical assessment of the long-term risk of fracture in patients with rheumatoid arthritis. Arthritis Rheum 2006; 54: 3104-3112
  • 31 Roux C. Osteoporosis in inflammatory joint diseases. Ost Int 2011; 22: 421-433
  • 32 Solomon DH, Goodson NJ, Katz JN et al. Patterns of cardiovascular risk in rheumatoid arthritis. Ann Rheum Dis 2006; 65: 1608-1612
  • 33 Baillet A, Zeboulon N, Gossec L et al. Efficacy of cardiorespiratory aerobic exercise in rheumatoid arthritis. Meta-analysis of randomized controlled trials. Arthritis Care Res 2010; 62: 984-992
  • 34 Scarvell J, Elkins MR. Aerobic exercise is beneficial for people with rheumatoid arthritis. Br J Sports Med 2011; 45: 1008-1009
  • 35 Stavropoulos-Kalinoglou A, Metsios GS, Veldhuizen van Zanten JJ et al. Individualised aerobic and resistance exercise training improves cardiorespiratory fitness and reduces cardiovascular risk in patients with rheumatoid arthritis. Ann Rheum Dis 2012; epub
  • 36 Lemmey AB, Marcora SM, Chester K et al. Effects of high-intensity resistance training in patients with rheumatoid arthritis: A randomized controlled trial. Arthritis Rheum 2009; 61: 1726-34
  • 37 Baillet A, Vaillant M, Guinot M et al. Efficacy of resistance exercises in rheumatoid arthritis: a meta-analysis of randomized controlled trials. Rheumatology 2012; 51: 519-27
  • 38 Hurkmans E, van der Giesen FJ, Vliet Vlieland TPM et al. Cochrane Database Syst Rev 2009; CD006853
  • 39 Strasser B, Leeb G, Strehblow C et al. The effects of strength and endurance training in patients with rheumatoid arthritis. Clin Rheumatol 2011; 30: 623-32
  • 40 De Jong Z, Munneke M, Zwinderman AH et al. Is a long-term high-intensity exercise program effective and safe in patients with rheumatoid arthritis?. Results of a randomized controlled trial. Arthritis and Rheumatism 2003; 48: 2415-24
  • 41 De Jong Z, Munneke M, Kroon HM et al. Long-term follow-up of a high-intensity exercise program in patients with rheumatoid arthritis. Clin Rheumatol 2009; 28: 663-671
  • 42 Van der Giesen FJ, van Lankveld W, Hopman-Rock M et al. Exploring the public health impact of an intensive exercise program for patients with rheumatoid arthritis. A dissemination and implementation study. Arthritis Care & Research 2010; 62: 865-872
  • 43 Cairns AP, McVeigh JG. A systematic review of the effects of dynamic exercise in rheumatoid arthritis. Rheumatol Int 2009; 30: 147-158
  • 44 Neill J, Belan I, Ried K. Effectiveness of non-pharmacological interventions for fatigue in adults with multiple sclerosis, rheumatoid arthritis, or systemic lupus erythematosus: a systematic review. J Advanced Nursing 2006; 56: 617-635
  • 45 Silva KNG, Imoto AM, Almeida GJM et al. Balance training (proprioceptive training) for patients with rheumatoid arthrits. Cochrane Database of Systematic Reviews 2010; CD007648
  • 46 Han A, Judd M, Welch V et al. Tai Chi for treating rheumatoid arthritis. Cochrane Database Syst Rev 2004; CD004849
  • 47 Lee MS, Pittler MH, Ernst E. Tai Chi für rheumatoid arthritis: a systematic review. Rheumatology 2007; 46: 1648-161
  • 48 Cooney JK, Law RJ, Matschke V et al. Benefits of exercise in rheumatoid arthritis. J Aging Research 2011; DOI: 10.4061/2011/681640.
  • 49 Law RJ, Markland DA, Jones JG et al. Perceptions of issues relating to exercise and joint health in rheumatoid arthritis: A UK-based questionnaire study. Musculoskeletal Care 2012; epub
  • 50 Hurkmans EJ, Jones A, Li LC et al. Quality appraisal of clinical guidelines on the use of physiotherapy in rheumatoid arthritis: a systematic review. Rheumatology 2011; 50: 1879-88
  • 51 Steultjens EM, Dekker J, Bouter LM et al. Occupational therapy for rheumatoid arthritis. Cochrane Database Syst Rev 2004; CD003114
  • 52 de Boer IG, Peeters AJ, Ronday HK et al. Assistive devices: usage in patients with rheumatoid arthritis. Clin Rheumatol 2009; 28: 119-128
  • 53 Macedo AM, Oakley SP, Panayi GS et al. Functional and work outcomes improve in patients with rheumatoid arthritis who receive targeted, comprehensive occupational therapy. Arthritis Rheum 2009; 61: 1522-1530
  • 54 Mathieux R, Marotte H, Battistine L et al. Early occupational therapy programme increases hand grip strength at 3 months : results from a randomised, blind, controlled study in early rheumatoid arthritis. Ann Rheum Dis 2009; 68: 400-403
  • 55 Egan M, Farmer M, Quimet MA et al. Spilnts and orthosis for treating rheumatoid arthritis. Cochrane Database Syst Rev 2003; CD004018
  • 56 Veehof MM, Taal E, Heijnsdijk-Rouwenhorst LM et al. Efficacy of wrist working splints in patients with rheumatoid arthritis: a randomized controlled study. Arthritis & Rheumatism 2008; 59: 1698-1704
  • 57 Silva AC, Jones A, Silva PG et al. Effectiveness of a night-time hand positioning splint in rheumatoid arthritis: a randomized controlled trial. J Rehabil Med 2008; 40: 749-754
  • 58 Adams J, Burridge J, Mullee M et al. The clinical effectiveness of static resting splints in early rheumatoid arthritis: a randomized controlled trial. Rheumatology 2008; 47: 1548-1553
  • 59 Wessel J. The effectiveness of hand exercises for persons with rheumatoid arthritis: a systematic review. J Hand Ther 2004; 17: 174-180
  • 60 Brorsson S, Hilliges M, Sollerman C et al. A six-week hand exercise programme improves strength and hand function in patients with rheumatoid arthritis. J Rehabil Med 2009; 41: 338-342
  • 61 Cima SR, Barone A, Porto JM et al. Strengthening exercises to improve hand strength and functionality in rheumatoid arthritis with hand deformities: a randomized, controlled study. Rheumatol Int 2012; epub
  • 62 Speed CA, Campbell R. Mechanisms of strength gain in a handgrip exercise programme in rheumatoid arthritis. Rheumatol Int 2012; 32: 159-63
  • 63 Macedo AM, Oakley SP, Panayi GS et al. Functional and work outcomes improve in patients with rheumatoid arthritis who receive targeted, comprehensive occupational therapy. Arthritis Rheum 2009; 61: 1522-30
  • 64 Göksel KA, Günaydin R, Adibelli ZH et al. Foot deformities in patients with rheumatoid arthritis: the relationship with foor functions. Int J Rheum Dis 2010; 13: 158-163
  • 65 Hawke F, Bums J, Radford JA et al. Custom-made foot orthoses for the treatment of foot pain. Cochrane Database Syst Rev 2008; CD006801
  • 66 Chang BC, Wang JY, Huang BS et al. Dynamic impression insole in rheumatoid foot with metatarsal pain. Clin Biomech 2012; 27: 196-201
  • 67 Pelland L, Brosseau L, Casimiro L et al. Electrical stimulation for the treatment of rheumatoid arthritis. Cochrane Database Syst Rev 2002; CD003687
  • 68 Casimiro L, Barnsley L, Brosseau L et al. Acupuncture and electroacupuncture for the treatment of rheumatoid arthritis. Cochrane Database of Systematic Reviews 2005; CD003788
  • 69 Casimiro L, Brosseau L, Welch V et al. Therapeutic ultrasound for the treatment of rheumatoid arthritis. Cochrane Database of Systematic Reviews 2002; CD003787
  • 70 Nakamura T, Fujihara S, Yamamoto-Nagata K et al. Low-intensity pulsed ultrasound reduces the inflammatory activity of synovitis. Ann Biomed Eng 2011; 39: 2964-71
  • 71 Brosseau L, Welch V, Wells GA et al. Low level laser therapy (classes I, II, and II) for treating rheumatoid arthritis. Cochrane Database of Systematic Reviews 2005; CD002049
  • 72 Meireles SM, Jones A, Jemmings F et al. Assessment of the effectiveness of low-level laser therapy on the hands of patients with rheumatoid arthritis: a randomized double-blind controlled trial. Clin Rheumatol 2010; 29: 501-509
  • 73 Alves AC, de Carvalho PD, Parente M et al. Low-level laser therapy in different stages of rheumatoid arthritis: a histological study. Lasers Med Sci 2012; epub
  • 74 Welch V, Brosseau L, Casimiro L et al. Thermotherapy for treating rheumatoid arthritis. Cochrane Database Syst Rev 2002; CD002826
  • 75 Oosterveld FGJ, Rasker JJ, Floors M et al. Infrared sauna in patients with rheumatoid arthritis and ankylosing spondylitis. Clin Rheumatol 2009; 28: 29-34
  • 76 Lee MS, Shin BC, Ernst E. Acupuncture for rheumatoid arthritis: a systematic review. Rheumatology 2008; 47: 1747-1753
  • 77 Wang C, de Pablo P, Chien X et al. Acupuncture for pain relief in patients with rheumatoid arthritis: a systematic review. Arthritis Rheum 2008; 59: 1249-1256
  • 78 Ouyang BS, Gao J, Che JL et al. Effect of electro-acupuncture on tumor necrosis factor-α and vascular endothelial growth factor in peripheral blood and joint synovia of patients with rheumatoid arthritis. Chin J Integr Med 2011; 17: 505-9
  • 79 Verhagen AP, Bierma-Zeinstra SMA, Cardoso JR et al. Balneotherapy for rheumatoid arthritis. Cochrane Database Syst Rev 2004; CD000518
  • 80 Yurtkuran M, Yurtkuran MA, Dilek K et al. A randomized, controlled study of balneotherapy in patients with rheumatois arthritis. Phys Rehab Kur Med 1999; 9: 92-6
  • 81 Franke A, Reiner L, Resch KL. Long-term benefit of radon spa therapy in the rehabilitation of rheumatoid arthritis: a randomized, double-blinded trial. Rheumatol Int 2007; 27: 703-713
  • 82 Hagen KB, Byfuglien MG, Falzon L et al. Dietary interventions for rheumatoid arthritis. Cochrane Database Syst Rev 2009; CD006400
  • 83 Smedslund G, Byfuglien MG, Olsen SU et al. Effectiveness and safetly of dietary interventions for rheumatoid arthritis: a systematic review of randomized controlled trials. J Am Diet Assoc 2010; 110: 727-735
  • 84 Cameron M, Gagnier JJ, Chrubasik S. Herbal therapy for treating rheumatoid arthritis. Cochrane Database of Syst Rev 2011; CD002948
  • 85 Goldbach-Mansky R, Wilson M, Fleischmann BD et al. Comparison of Tripterygium wilfordii Hook F versus sulfasalazine in the treatment of rheumatoid arthritis: a randomized trial. Ann Int Med 2009; 151: 229-240
  • 86 Astin JA, Beckner W, Soeken K et al. Psychological interventions for rheumatoid arthritis: a meta-analysis of randomized controlled trials. Arthritis Rheum 2002; 47: 291-302
  • 87 Riemsma RP, Kirwan JR, Taal E et al. Patient education for adults with rheumatoid arthritis. Cochrane Database of Syst Rev 2003; CD003688
  • 88 Edwards RR, Giles J, Birmingham III CO et al. Moderators of the negative effects of catastrophizing in arthritis. Pain Medicine 2010; 11: 591-599