Planta Medica, Table of Contents Planta Med 2012; 78(18): 1971-1975DOI: 10.1055/s-0032-1327875 Natural Product Chemistry Letters Georg Thieme Verlag KG Stuttgart · New York Unusual 9,19 : 24,32-Dicyclotetracyclic Triterpenoids from Lygodium japonicum Qing-hua Han 1 School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, China , Xin Liu 1 School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, China , Wen-qing Yao 2 School of Chemistry and Biological Science, University of Science and Technology, Beijing, China , Zhong-bin Cheng 1 School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, China , Ting-ting Lin 1 School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, China , Ching Song 2 School of Chemistry and Biological Science, University of Science and Technology, Beijing, China , Sheng Yin 1 School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, China › Author Affiliations Recommend Article Abstract Buy Article Abstract Lygodipenoids A (1) and B (2), two novel C33 tetracyclic triterpenoids with a new 9,19 : 24,32-dicyclopropane skeleton, were isolated from the whole grass of Lygodium japonicum. Their structures were elucidated by spectroscopic and chemical means. Compounds 1 and 2 were tested in transfected cultured human embryonic kidney 293 HEK293 cells for an agonist assay, and compound 1 was identified as a partial agonist for liver X receptor α. Key words Key words>Lygodium japonicum (Thunb.) Sw. - Lygodiaceae - 9,19 : 24,32-dicyclotetracyclic triterpenoid - liver X receptor α Full Text References References 1 Qin RC, Fu SJ, Wang ZH, Xing GX. Flora of China, Vol. 2. Beijing: Science Press; 1959: 105-113 2 Chen LJ, Zhang GG, He J, Guan J, Pan CY, Mi WZ, Wang Q. New naphthoquinone from the root of Lygodium japonicum (Thunb.) Sw. J Nat Med 2010; 64: 114-116 3 Zhu LX, Zhang GG, Chen LJ, Wang SC, Li P, Li L. A new ecdysteroside from Lygodium japonicum (Thunb.) Sw. J Nat Med 2009; 63: 215-219 4 Ye WC, Fan CL, Zhang LH, Yin ZQ, Zhao SX. A new phenolic glycoside from the roots of Lygodium japonicum . Fitoterapia 2007; 78: 600-601 5 Wynne G, Mander LN, Goto N, Yamane H, Omori T. 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