Die Wirkung von Pflanzenstoffen auf parodontalpathogene Bakterien

Das Ziel der vorliegenden Studie war es, die Wirkung verschiedener Pflanzenextrakte auf das Wachstum parodontalpathogener Bakterien zu untersuchen. Zur Bestimmung des antibakteriellen Effekts von Ingwer (Zingiber officinalis), Salbei (Salvia officinalis), Kamille (Chamomilla recutita), Rosmarin (Rosmarinus officinalis), Nelke (Syzygium aromaticum), Myrrhe (Commiphora abyssinica) und Rathania (Krameria lappacea) gegenüber Fusobacterium nucleatum ATCC 10 953, Porphyromonas gingivalis ATCC 33 277, Actinobacter actinomycetemcomitans ATCC 33 384 und Enterococcus faecalis ATCC 29 212 wurde der Agar-Diffusionstest verwendet. Das Bakterienwachstum konnte durch die meisten Pflanzenextrakte in unterschiedlichem Maße gehemmt werden. Der Nelkenextrakt wies die höchste antibakterielle Wirksamkeit auf, welche teilweise die von Chlorhexidin (Positivkontrolle) übertraf. Die vorliegenden Ergebnisse zeigen, dass Pflanzenstoffe die antibakterielle Parodontitis-Therapie sinnvoll unterstützen könnten.

The aim of this study was to evaluate the inhibition activity of different plant extracts on periodonto-pathogenic bacteria. Supercritical CO₂-extracts from Zingiber officinalis (ginger), Salvia officinalis (sage), Chamomilla recutita (camomile), Rosmarinus officinalis (rosemary), Syzygium aromaticum (clove), Krameria lappacea (rathania), and Commiphora abyssinica (myrrh) were tested against Fusobacterium nucleatum ATCC 10 953, Porphyromonas gingivalis ATCC 33 277, Aggregatibacter actinomycetemcomitans ATCC 33 384, and Enterococcus faecalis ATCC 29 212. The antimicrobial activity was determined by the agar diffusions method and the zones of growth inhibition were measured. The bacterial growth was inhibited through the most plant extracts in different extent. The clove extract showed the highest antibacterial effects, which increased the effect of CHX (positive control) partially. The results suggest that the application of special plant extracts may be helpful as adjunct treatment to inactivate periodonto-pathogenic bacteria.

Schlüsselwörter

Pflanzenstoffe - Parodontitis - Nelkenextrakt - Ingwer –F. nucleatum - P. gingivalis

Key words

Plant Extracts - Periodontitis - Clove - Ginger - F. nucleatum - P. gingivalis

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