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Synthesis 2013; 45(24): 3325-3331
DOI: 10.1055/s-0033-1338562
DOI: 10.1055/s-0033-1338562
short review
Synthetic Developments on the Indolizidine Alkaloid, Harmicine
Further Information
Publication History
Received: 21 August 2013
Accepted after revision: 28 October 2013
Publication Date:
21 November 2013 (online)
Abstract
Indolizidine alkaloids are widespread in Nature and display a wide spectrum of biological activity. Harmicine, as an example of an indolizidine alkaloid, shows antileishmanial and antinociceptive activity, and is an interesting target for synthetic organic chemists. This article provides a comprehensive review of the synthetic routes toward harmicine since its isolation in 1997.
1 Introduction
2 Synthetic Approaches
3 Conclusions
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