Convenient Synthesis of Benzoxazolone Derivatives by Cross-Coupling of Benzoxazolone Boronates with Aryl Halides

Abstract

Benzoxazolone derivatives with various substituents at the C-5 position were synthesized efficiently via benzoxazolone boronates as the key intermediate. The target compounds were also synthesized from (het)aryl halides in a one-pot process. These methods permitted efficient exploratory syntheses of a series of benzoxazolone derivatives.

Key words

heterocycles - boron - cross-coupling - biaryls - catalysis - arylations

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