Preparation of Aromatic Triazenes and Their Application in Silver-Mediated Perfluoroalkylation Reactions

Andreas Hafner; Christoph Hussal; Stefan Bräse

doi:10.1055/s-0033-1341249

Synthesis, Inhaltsverzeichnis

Synthesis 2014; 46(11): 1448-1454
DOI: 10.1055/s-0033-1341249

practical synthetic procedures

Preparation of Aromatic Triazenes and Their Application in Silver-Mediated Perfluoroalkylation Reactions

Andreas Hafner

^aInstitute of Organic Chemistry, KIT-Campus South, Fritz-Haber-Weg 6, 76131 Karlsruhe, Germany Fax: +49(721)60848581 eMail: braese@kit.edu

,

Christoph Hussal

^aInstitute of Organic Chemistry, KIT-Campus South, Fritz-Haber-Weg 6, 76131 Karlsruhe, Germany Fax: +49(721)60848581 eMail: braese@kit.edu

,

Stefan Bräse*

^aInstitute of Organic Chemistry, KIT-Campus South, Fritz-Haber-Weg 6, 76131 Karlsruhe, Germany Fax: +49(721)60848581 eMail: braese@kit.edu

^bInstitute of Toxicology and Genetics, KIT, Campus-North, Hermann-von-Helmholtz Platz 1, 76344 Eggenstein-Leopoldshafen, Germany

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Abstract

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Abstract

Herein, the syntheses of various functionalized 1,3-diisopropyltriaz-1-enes is described. This simple transformation tolerates a vast number of functional groups (e.g., halides) and allows the syntheses of 1,3-diisopropyltriaz-1-enes starting from commercially available aniline derivatives. These substrates are suitable for a range of silver-mediated perfluoroalkylation reactions.

Key words

alkylation - triazene - perfluoroalkylation - silver - synthetic methods

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Referenzen

References

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