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DOI: 10.1055/s-0033-1360295
Therapieentscheidung bei Patienten mit operablem, nicht metastasiertem Ösophaguskarzinom
Therapeutic Decisions in Patients with Operable, Non-Metastatic Oesophageal CancerPublication History
Publication Date:
28 February 2014 (online)
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Zusammenfassung
Hintergrund: Die Therapie des Ösophaguskarzinoms wird kontrovers diskutiert. Gegenstand
dieser Arbeit sind die Therapieoptionen beim operablen, nicht metastasierten Ösophaguskarzinom.
Material und Methoden: Aktuelle Literaturrecherche über die verschiedenen
Behandlungsoptionen beim klassischen Ösophaguskarzinom.
Ergebnisse: Das Ösophaguskarzinom
wird nach multiplen Kriterien therapiert. Die Ösophagektomie im multimodalen Setting hat das
beste Outcome. Die definitive Radiochemotherapie als konservatives Regime bietet Risikopatienten
eine Therapiealternative.
Schlussfolgerung: Die Therapieentscheidung bei Patienten mit
operablem, nicht metastasiertem Ösophaguskarzinom muss anhand eines standardisierten Stagings
und nach Abklärung aller Risikofaktoren erfolgen.
Abstract
Background: Therapy for oesophageal carcinoma is a subject of controversial debate. The
aim of this study is to answer the question how the therapeutic decision in patients with
operable, non-metastatic oesophageal cancer should be made.
Materials and Methods: A
systematic literature research regarding different therapeutic strategies in patients with
oesophageal cancer was undertaken.
Results: Multiple criteria influence the therapy for
oesophageal carcinoma. Radical oesophagectomy in a multimodal setting is the therapy of choice.
Definitive chemoradiation is a conservative option for high risk patients.
Conclusion:
Therapeutic decisions in patients with oesophageal cancer should only be made after standardised
staging and accurate risk analysis.
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