Gastroenterologie up2date, Inhaltsverzeichnis Gastroenterologie up2date 2014; 10(02): 77-78DOI: 10.1055/s-0034-1365803 Klinisch-pathologische Konferenz © Georg Thieme Verlag KG Stuttgart · New York Multifokale maligne Transformation β-Catenin-aktivierter hepatozellulärer Adenome nach Missbrauch anaboler Steroide Nina Waldburger , Peter Schirmacher , Thomas Longerich Artikel empfehlen Abstract Artikel einzeln kaufen Alle Artikel dieser Rubrik Volltext Referenzen Literatur 1 Edmondson HA, Henderson B, Benton B. Liver-cell adenomas associated with use of oral contraceptives. N Engl J Med 1976; 294: 470-472 2 Bioulac-Sage P, Rebouissou S, Thomas C et al. Hepatocellular adenoma subtype classification using molecular markers and immunohistochemistry. Hepatology 2007; 46: 740-748 3 Bioulac-Sage P, Laumonier H, Couchy G et al. Hepatocellular adenoma management and phenotypic classification: the Bordeaux experience. Hepatology 2009; 50: 481-489 4 Nault JC, Zucman Rossi J. Molecular classification of hepatocellular adenomas. Int J Hepatol 2013; 2013: 315947 5 Rebouissou S, Amessou M, Couchy G et al. Frequent in-frame somatic deletions activate gp130 in inflammatory hepatocellular tumours. Nature 2009; 457: 200-204 6 Pilati C, Amessou M, Bihl MP et al. Somatic mutations activating STAT3 in human inflammatory hepatocellular adenomas. J Exp Med 2011; 208: 1359-1366 7 Nault JC, Fabre M, Couchy G et al. GNAS-activating mutations define a rare subgroup of inflammatory liver tumors characterized by STAT3 activation. J Hepatol 2012; 56: 184-191 8 Bioulac-Sage P, Cubel G, Taouji S et al. Immunohistochemical markers on needle biopsies are helpful for the diagnosis of focal nodular hyperplasia and hepatocellular adenoma subtypes. Am J Surg Pathol 2012; 36: 1691-1699 9 Evason KJ, Grenert JP, Ferrell LD et al. Atypical hepatocellular adenoma-like neoplasms with beta-catenin activation show cytogenetic alterations similar to well-differentiated hepatocellular carcinomas. Hum Pathol 2013; 44: 750-758 10 Bedossa P, Burt AD, Brunt EM et al. Well-differentiated hepatocellular neoplasm of uncertain malignant potential: proposal for a new diagnostic category. Hum Pathol 2014; 45: 658-660