Useful Methods for Targeted Plant Selection in the Discovery of Potential New Drug Candidates

Sianne L. Schwikkard; Dulcie A. Mulholland

doi:10.1055/s-0034-1368549

Planta Medica, Inhaltsverzeichnis

Planta Med 2014; 80(14): 1154-1160
DOI: 10.1055/s-0034-1368549

Perspectives

Georg Thieme Verlag KG Stuttgart · New York

Useful Methods for Targeted Plant Selection in the Discovery of Potential New Drug Candidates

Sianne L. Schwikkard

¹Natural Products Research Group, Department of Chemistry, Faculty of Engineering and Physical Sciences, University of Surrey, Guildford, Surrey, United Kingdom

²School of Chemistry and Physics, University of KwaZulu-Natal, Durban, South Africa

,

Dulcie A. Mulholland

¹Natural Products Research Group, Department of Chemistry, Faculty of Engineering and Physical Sciences, University of Surrey, Guildford, Surrey, United Kingdom

²School of Chemistry and Physics, University of KwaZulu-Natal, Durban, South Africa

› Institutsangaben

Abstract

The efficient and effective selection of appropriate plants for investigative purposes in a drug discovery program is of crucial importance for a successful outcome. A variety of approaches have been used by researchers with varying levels of success. A variety of different approaches to plant selection are discussed, including the ethnomedicinal approach, some ecological approaches, and the use of combinatorial and computational methodologies.

Key words

biodiversity - targeted selection - ethnomedicine - drug discovery

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Referenzen

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