Subscribe to RSS
Please copy the URL and add it into your RSS Feed Reader.
https://www.thieme-connect.de/rss/thieme/en/10.1055-s-00000084.xml
Synthesis 2015; 47(03): 429-438
DOI: 10.1055/s-0034-1379955
DOI: 10.1055/s-0034-1379955
paper
The Oxidative Cross-Coupling of Benzonitriles with Multiform Substrates: A Domino Strategy Inspired Easy Access to α-Ketoimides
Further Information
Publication History
Received: 18 October 2014
Accepted after revision: 06 December 2014
Publication Date:
14 January 2015 (online)
This work is dedicated to our mentor Prof. P. M. Bhate on the occasion of his 61st birthday.
Abstract
An iodine-promoted highly efficient convergent synthesis of α-ketoimides from multiform substrates and benzonitriles through oxidative imidation reaction is described. This domino oxidative imidation process involves cleavage of C–H bond and construction of C–O and C–N bonds. This method could be a powerful compliment to the existing methods owing to its use of abundantly available starting materials and reagents.
Supporting Information
- Supporting information for this article is available online at http://dx.doi.org/10.1055/s-0034-1379955.
- Supporting Information