DMW – Klinischer Fortschritt, Table of Contents Dtsch Med Wochenschr 2014; 139(49): 2507-2509DOI: 10.1055/s-0034-1387401 Infektiologie | Commentary Infektiologie © Georg Thieme Verlag KG Stuttgart · New York Morbus Whipple Whipple’s disease V. Moos 1 Medizinische Klinik I, Charité Berlin , T. Schneider 1 Medizinische Klinik I, Charité Berlin › Author Affiliations Recommend Article Abstract Buy Article Schlüsselwörter SchlüsselwörterMorbus Whipple - Tropheryma whipplei - gastrointestinale Infektion - inflammatorisches Immunrekonstitutionssyndrom (IRIS) Keywords KeywordsWhipple’s disease - Tropheryma whipplei - gastrointestinal infection - immune reconstitution inflammatory syndrome (IRIS) Full Text References Literatur 1 Fenollar F, Laouira S, Lepidi H et al. Value of Tropheryma whipplei quantitative polymerase chain reaction assay for the diagnosis of Whipple disease: usefulness of saliva and stool specimens for first-line screening. Clin Infect Dis 2008; 47: 659-667 2 Fenollar F, Trani M, Davoust B et al. Prevalence of asymptomatic Tropheryma whipplei carriage among humans and nonhuman primates. J Infect Dis 2008; 197: 880-887 3 Fenollar F, Trape JF, Bassene H et al. Tropheryma whipplei in fecal samples from children, Senegal. Emerg Infect Dis 2009; 15: 922-924 4 Feurle GE, Junga NS, Marth T. Efficacy of ceftriaxone or meropenem as initial therapies in Whipple's disease. Gastroenterology 2010; 138: 478-486 5 Feurle GE, Moos V, Blaker H et al. Intravenous ceftriaxone, followed by 12 or three months of oral treatment with trimethoprim-sulfamethoxazole in Whipple's disease. J Infect 2013; 66: 263-270 6 Feurle GE, Moos V, Schneider T et al. The combination of chloroquine and minocycline, a therapeutic option in cerebrospinal infection of Whipple's disease refractory to treatment with ceftriaxone, meropenem and co-trimoxazole. J Antimicrob Chemother 2012; 67: 1295-1296 7 Keita AK, Brouqui P, Badiaga S et al. Tropheryma whipplei prevalence strongly suggests human transmission in homeless shelters. Int J Infec Dis 2013; 17: e67-68 8 Lagier JC, Lepidi H, Raoult D et al. Systemic Tropheryma whipplei: clinical presentation of 142 patients with infections diagnosed or confirmed in a reference center. Medicine 2010; 89: 337-345 9 Marth T, Raoult D. Whipple's disease. Lancet 2013; 361: 239-246 10 Raoult D, Fenollar F, Rolain JM et al. Tropheryma whipplei in children with gastroenteritis. Emerg Infec Dis 2010; 16: 776-782 11 Schneider T, Moos V, Loddenkemper C et al. Whipple's disease: new aspects of pathogenesis and treatment. Lancet Infect Dis 2008; 8: 179-190 12 Von Herbay A. [Whipple's disease. Histologic diagnosis after the discovery of Tropheryma whippelii]. Pathologe 2001; 22: 82-88 13 Von Herbay A, Maiwald M, Ditton HJ et al. Histology of intestinal Whipple's disease revisited. A study of 48 patients. Virchows Arch 1996; 429: 335-343