Psychother Psychosom Med Psychol 2015; 65(01): 33-35
DOI: 10.1055/s-0034-1394404
Übersicht
© Georg Thieme Verlag KG Stuttgart · New York

Welche Bedeutung haben die Ernährungswissenschaften für die Behandlung der Anorexia nervosa?

Nutrition Sciences in the Treatment of Eating Disorders
Verena Haas
1   Klinik für Psychiatrie, Psychosomatik und Psychotherapie des Kindes- und Jugendalters, Charité-Universitätsmedizin Berlin
2   Medizinische Klinik mit Schwerpunkt Psychosomatik, Campus Benjamin Franklin, Charité-Universitätsmedizin Berlin
,
Michael Boschmann
3   Experimental and Clinical Research Center (ECRC) Campus Buch, Charité-Universitätsmedizin Berlin
› Author Affiliations
Further Information

Publication History

eingereicht06 October 2014

akzeptiert 09 October 2014

Publication Date:
16 January 2015 (online)

Zusammenfassung

Mehrere Studien liefern Hinweise auf einen biologisch bedingten Hypermetabolismus bei Patientinnen mit Anorexia nervosa (AN) während und kurz nach erfolgreicher Gewichtszunahme. Wie ein entsprechend erhöhter Energiebedarf mit derzeit praktizierten ernährungstherapeutischen Behandlungsstrategien in Einklang gebracht werden kann, ist bislang ungewiss. Wenn es gelingt, die pathophysiologischen Besonderheiten der Energieverwertung von AN-Patientinnen besser zu verstehen, könnten diese Patientinnen in Zukunft ernährungstherapeutisch besser begleitet werden. An dieser Stelle kann evidenzbasierte, ernährungswissenschaftliche Forschung einen essentiellen Beitrag leisten.

Abstract

Several studies provide evidence for the existence of a hypermetabolic state of biological origin in recently weight recovered patients with anorexia nervosa. It remains unclear if current nutritional rehabilitation strategies are consistent with the resulting high energy requirements. Further insight into specific pathophysiological characteristics of energetic efficiency in patients with anorexia nervosa will help us to provide evidence based nutritional guidance. Basic nutritional research in this field is urgently required.

 
  • Literatur

  • 1 Position of the American Dietetic Association . Nutrition Intervention in the Treatment of Anorexia nervosa, Bulimia nervosa, and Other Eating Disorders. J Am Diet Assoc 2006; 106: 2073-2082
  • 2 Setnick J. Micronutrient Deficiencies and Supplementation in Anorexia and Bulimia nervosa: A Review of Literature. Nutr Clin Pract 2010; 25: 137-142
  • 3 Marzola E, Nasser JA, Hashim SA et al. Nutritional rehabilitation in anorexia nervosa: review of the literature and implications for treatment. BMC Psychiatry 2013; 13: 290
  • 4 Vignaud M, Constantin JM, Ruivard M et al. Refeeding syndrome influences outcome of anorexia nervosa patients in intensive care unit: an observational study. Critical Care 2010; 14: R172
  • 5 National Institute for Health and Clinical Excellence . Nutrition support in adults: full guideline (CG32)
  • 6 Royal College of Physicians . MARSIPAN: Management of really sick patients with Anorexia nervosa College Report CR162, October 2010;
  • 7 Royal College of Psychiatrists, London 2005 . Guidelines for the nutritional management of anorexia nervosa 2005;
  • 8 Mehler PS, Winkelman AB, Andersen DM et al. Nutritional rehabilitation: practical guidelines for refeeding the anorectic patient. J Nutr Metab 2010; 2010
  • 9 American Dietetic Association . Nutrition Intervention in the Treatment of Eating Disorders. Practice Paper 2012;
  • 10 Kaye WH, Gwirtsman HE, Obarzanek E et al. Relative importance of calorie intake needed to gain weight and level of physical activity in anorexia nervosa. Am J Clin Nutr 1988; 47: 989-994
  • 11 Dempsey DT, Crosby LO, Pertschuk MJ et al. Weight gain and nutritional efficacy in anorexia nervosa. Am J Clin Nutr 1984; 39: 236-242
  • 12 Weltzin TE, Fernstrom MH, Hansen D et al. Abnormal caloric requirements for weight maintenance in patients with anorexia and bulimia nervosa. Am J Psychiatry 1991; 148: 1675-1682
  • 13 D-A-CH: Referenzwerte für die Nährstoffzufuhr
  • 14 Van Wymelbeke V, Brondel L, Marcel Brun J et al. Factors associated with the increase in resting energy expenditure during refeeding in malnourished anorexia nervosa patients. Am J Clin Nutr 2004; 80: 1469-1477
  • 15 Haas V, Onur S, Paul T et al. Leptin and body weight regulation in patients with anorexia nervosa before and during weight recovery. Am J Clin Nutr 2005; 81: 889-896
  • 16 Moukkadem M, Boulier A, Apfelbaum M et al. Increase in diet-induced thermogenesis at the start of refeeding in severely malnourished anorexia nervosa patients. Am J Clin Nutr 1997; 66: 133-140
  • 17 Exner C, Hebebrand J, Remschmidt H et al. Leptin suppresses semi-starvation induced hyperactivity in rats: implications for anorexia nervosa. Mol Psychiatry 2000; 5: 476-481
  • 18 Carrera O, Adan RAH, Guitierrez E et al. Hyperactivity in anorexia nervosa: warming up not just burning-off calories. PLoS One 2012; 7: e41851
  • 19 Miller DS, Mumford P. Gluttony. 1. An experimental study of overeating low- or high-protein diets. Am J Clin Nutr 1967; 20: 1212-1222
  • 20 Leibel RL, Rosenbaum M, Hirsch J. Changes in energy expenditure resulting from altered body weight. N Engl J Med 1995; 332: 621-628
  • 21 Levine JA, Eberhardt NL, Jensen MD. Role of nonexercise activity thermogenesis in resistance to fat gain in humans. Science 1999; 283: 212-214