New Chiral Benzimidazoles Derived from 1,2-Diaminocyclohexane

Abstract

A simple synthesis of new enantiomeric benzimidazoles was developed. Starting from readily available enantiomeric trans-1,2-diaminocyclohexane, the respective products were obtained in 3–4 steps in moderate to fair yields. A series of ten benzimidazoles substituted at the position 2 with alkyl, aryl, and heteroaryl groups were prepared.

Key words

benzimidazoles - chirality - heterocycles - ring closure - ligands

• References


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