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Synthesis 2016; 48(12): 1920-1926
DOI: 10.1055/s-0035-1561950
DOI: 10.1055/s-0035-1561950
special topic
Copper-Catalyzed Aerobic Oxidative Cyclization of Ketoxime Acetates with Pyridines for the Synthesis of Imidazo[1,2-a]pyridines
Authors
Further Information
Publication History
Received: 24 January 2016
Accepted after revision: 23 February 2016
Publication Date:
29 March 2016 (online)
Abstract
A copper(I)-catalyzed aerobic oxidative coupling of ketoxime acetates with simple pyridines for the synthesis of imidazo[1,2-a]pyridines has been developed. This reaction tolerates a wide range of functional groups and it affords a series of valuable imidazo[1,2-a]pyridines in high yields under mild conditions.
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- Supporting information for this article is available online at http://dx.doi.org/10.1055/s-0035-1561950.
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