Abstract
Background A considerable proportion of patients with acute infective endocarditis require surgical
treatment. The aim of this study was to collate our short- and medium-term results
of surgical treatment of infective endocarditis and to compare the results in native
and prosthetic endocarditis.
Method Total 254 operations for infective endocarditis from January 2008 to May 2015 were
included in this retrospective study. There were 182 operations for native valve endocarditis
and 72 for prosthetic valve endocarditis. Patient characteristics, operative details,
complications, and mortality were registered.
Results The endocarditis was left sided in 247 operations (146 aortic, 78 mitral, and 23
double-valve) and right-sided in 7 (5 tricuspid and 2 pulmonary). Twenty-two patients
(8.7%) died within 30 days (7.7% with native valve endocarditis and 11.1% with prosthetic
valve endocarditis, p = 0.31). Severe perioperative complications occurred in 99 of 254 operations (39%).
Overall cumulative survival at 1 and 5 years was 86% and 75%, respectively, and it
was not significantly different for native and prosthetic endocarditis (p = 0.31). Eighteen patients (8%) had one (n = 16) or two (n = 2) recurrent episodes of endocarditis requiring surgery.
Conclusion Surgery for infective endocarditis is still associated with a high early mortality
rate and a considerable complication rate. Long-term outcome is acceptable. In our
study population, morbidity and mortality were not significantly different in native
and prosthetic endocarditis.
Keywords
aortic valve and root - heart valve surgery - prosthetic valve endocarditis - native
valve endocarditis - surgical treatment of endocarditis - valve disease
