Carbene-Type Species in the Functionalization of Porphyrin Derivatives

Ana T. P. C. Gomes; Luana da S. M. Forezi; Mário M. Q. Simões; Daniel T. Gonzaga; Mariana F. C. Cardoso; Fernando de C. Da Silva; Maria G. P. M. S. Neves; Vítor F. Ferreira; José A. S. Cavaleiro

doi:10.1055/s-0037-1609756

Synthesis, Table of Contents

Synthesis 2018; 50(14): 2678-2692
DOI: 10.1055/s-0037-1609756

short review

Carbene-Type Species in the Functionalization of Porphyrin Derivatives

Ana T. P. C. Gomes*

^aDepartment of Chemistry and QOPNA, University of Aveiro, 3810-193 Aveiro, Portugal Email: ana.peixoto@ua.pt

,

Luana da S. M. Forezi*

^bDepartamento de Química Orgânica, Instituto de Química, Universidade Federal Fluminense, 24020-150 Niterói, RJ, Brazil Email: luanaforezi@hotmail.com

,

Mário M. Q. Simões

^aDepartment of Chemistry and QOPNA, University of Aveiro, 3810-193 Aveiro, Portugal Email: ana.peixoto@ua.pt

,

Daniel T. Gonzaga

^bDepartamento de Química Orgânica, Instituto de Química, Universidade Federal Fluminense, 24020-150 Niterói, RJ, Brazil Email: luanaforezi@hotmail.com

,

Mariana F. C. Cardoso

^bDepartamento de Química Orgânica, Instituto de Química, Universidade Federal Fluminense, 24020-150 Niterói, RJ, Brazil Email: luanaforezi@hotmail.com

,

Fernando de C. Da Silva

^bDepartamento de Química Orgânica, Instituto de Química, Universidade Federal Fluminense, 24020-150 Niterói, RJ, Brazil Email: luanaforezi@hotmail.com

,

Maria G. P. M. S. Neves

^aDepartment of Chemistry and QOPNA, University of Aveiro, 3810-193 Aveiro, Portugal Email: ana.peixoto@ua.pt

,

Vítor F. Ferreira

^cDepartamento de Tecnologia Farmacêutica, Faculdade de Farmácia, Universidade Federal Fluminense, Niterói, RJ, 24241-002, Brazil

,

José A. S. Cavaleiro

^aDepartment of Chemistry and QOPNA, University of Aveiro, 3810-193 Aveiro, Portugal Email: ana.peixoto@ua.pt

› Author Affiliations

Abstract

All articles of this category

Abstract

Carbenes and NHCs play an important role in porphyrin chemistry and several synthetically useful transformations leading to the preparation of new porphyrin derivatives have been developed. This short review presents an overview covering the literature from 2007–2017, on the role of these transient species in the functionalization of porphyrin macrocycles.

Key words

porphyrin - carbene - NHC - cyclopropanation - X–H insertion

Full Text

References

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