Download PDF
Thromb Haemost 2002; 88(05): 882
DOI: 10.1055/s-0037-1613324
Letters to the Editor
Schattauer GmbH

The Fibrinolytic System and Obesity

H.R. Lijnen
1   Center for Molecular and Vascular Biology, University of Leuven, Leuven, Belgium
,
I. Juhan-Vague
2   Haematology Laboratory, CHU Timone and INSERM EPI 9936, Marseille, France
› Author Affiliations
Further Information

Publication History

Received 29 July 2002

Accepted 29 July 2002

Publication Date:
08 December 2017 (online)

Also available at
    Permissions and Reprints

 

 

  • References

  • 1 Hoover-Plow J, Ellis J, Yuen L. In vivo plasminogen deficiency reduces fat accumulation. Thromb Haemost 2002; 87: 1011-9.
    Thieme ConnectPubMedSearch in Google Scholar
  • 2 Juhan-Vague I, Alessi MC. Regulation of fibrinolysis in the development of atherothrombosis: role of adipose tissue. Thromb Haemost 1999; 82: 832-6.
    Thieme ConnectPubMedSearch in Google Scholar
  • 3 Samad F, Loskutoff DJ. Hemostatic gene expression and vascular disease in obesity: insights from studies of genetically obese mice. Thromb Haemost 1999; 82: 742-7.
    Thieme ConnectPubMedSearch in Google Scholar
  • 4 Lijnen HR. Plasmin and matrix metalloproteinases in vascular remodeling. Thromb Haemost 2001; 86: 324-33.
    Thieme ConnectPubMedSearch in Google Scholar
  • 5 Morange PE, Lijnen HR, Alessi MC, Kopp F, Collen D, Juhan-Vague I. Influence of PAI-1 on adipose tissue growth and on metabolic parameters in a murine model of diet-induced obesity. Arterioscler Thromb Vasc Biol 2000; 20: 1150-4.
    CrossrefPubMedSearch in Google Scholar
  • 6 Eren M, Su M, Atkinson J, King L, Declerck P, Vaughan DE. Phenotypic derangements associated with overexpression of plasminogen activator inhibitor-1 (PAI-1) in transgenic mice. Arterioscler Thromb Vasc Biol 2001; 21: 695 (Abstr. 230).
    PubMedSearch in Google Scholar
  • 7 Schafer K, Fujisawa K, Konstantinides S, Loskutoff J. Disruption of the plasminogen activator inhibitor 1 gene reduces the adiposity and improves the metabolic profile of genetically obese and diabetic ob/ob mice. FASEB J 2001; 15: 1840-2.
    CrossrefPubMedSearch in Google Scholar
  • 8 Morange PE, Bastelica D, Bonzi MF, Van Hoef B, Collen D, Juhan-Vague I, Lijnen HR. Influence of t-PA and u-PA on adipose tissue development in a murine model of diet-induced obesity. Thromb Haemost 2002; 87: 306-10.
    Thieme ConnectPubMedSearch in Google Scholar
  • 9 Coleman DL. Diabetes-obesity syndromes in mice. Diabetes 1982; 31: 1-6.
    CrossrefPubMedSearch in Google Scholar
  • 10 West DB, Boozer CN, Moody DL, Atkinson RL. Dietary obesity in nine inbred mouse strains. Am J Physiol 1992; 262: R1025-R32.
    PubMedSearch in Google Scholar
  • 11 Surwit RS, Feinglos MN, Rodin J, Sutherland A, Petro AE, Opara EC, Kuhn CM, Rebuffe-Scrive M. Differential effects of fat and sucrose on the development of obesity and diabetes in C57BL/6J and A/J mice. Metabolism 1995; 44: 645-51.
    CrossrefPubMedSearch in Google Scholar
  • 12 Valet P, Tavernier G, Castan-Laurell I, Saulnier-Blache JS, Langin D. Understanding adipose tissue development from transgenic animal models. J Lipid Res 2002; 43: 835-60.
    PubMedSearch in Google Scholar